The Mozart Effect: A quantitative EEG study

Verrusio, Walter; Ettorre, Evaristo; Vicenzini, Edoardo; Vanacore, Nicola; Cacciafesta, Mauro; Mecarelli, Oriano

doi:10.1016/j.concog.2015.05.005

Cited by 74 publications

(60 citation statements)

References 28 publications

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“…These EEG waves are linked to memory, cognition and processing speed to solving problems; however, no EEG changes were observed in the same populations after listening to "Fur Elise" sonata by Beethoven. The authors conclude that this Mozart's music activates by unknown mechanisms neuronal circuits related to attention and cognition [56]. A further support to this Mozart effect on the brain, comes from recent studies demonstrating that listening to this sonata K448 decreases the number and severity of drug-refractory epileptic encephalopathies in children and young adults [57][58][59].…”

Section: Discussionmentioning

confidence: 69%

Cognitive Evolution of a Patient Who Suffered a Subarachnoid Haemorrhage Eight Years Ago, after Being Treated with Growth Hormone, Melatonin and Neurorehabilitation

Quintana¹,

Agra²,

Outeiral³

et al. 2018

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Abstract:To describe the cognitive evolution of a patient who suffered a subarachnoid haemorrhage resulting in a total loss of his cognitive functions. The patient was initially treated with GH (0.8 mg/day), melatonin (50 mg/day) and neurorehabilitation 1 year after his brain damage, during 3 months. Then continued with GH (0.5 mg/day, 6 months/year, during 2 years) and melatonin treatments and neurorehabilitation (3 days/week). 5 years later the patient came back to our Centre due to the absence of recent memory and personal and spatio-temporal orientation and he received an intensive specific neurorehabilitation, including EINA (Auditory Stimulation and Neurosensory Integration), together with GH (0.8 mg/day) and melatonin, for 6 months. At discharge of his first treatment period cognitive functions showed very poor changes but these had been improved when he came back 5 years later. A review carried out 8 years after SHA demonstrated that the patient significantly recovered in all the cognitive functions and he was able to live an independent life. GH plays a key role on cognition, including its actions on recent memory. Melatonin, in turn, helps as a neuroprotective agent. A specific neurostimulation must be performed so that the effects of GH can be expressed. Within neurostimulation, EINA seems to play a very important role for enhancing the effects of medical and rehabilitative treatments on brain plasticity.

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Section: Discussionmentioning

confidence: 69%

Cognitive Evolution of a Patient Who Suffered a Subarachnoid Haemorrhage Eight Years Ago, after Being Treated with Growth Hormone, Melatonin and Neurorehabilitation

Quintana¹,

Agra²,

Outeiral³

et al. 2018

Reports

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“…(Eisenberg, 1999) Semakin banyak rangsangan dari lingkungan makin banyak sinaps yang akan terbentuk dan makin banyak jumlah sel neuron yang akan bertahan (Bures, 1988) Dasar ilmiah dari proses diatas adalah bahwa rangsangan suara atau musik dapat mengurangi jumlah proses kematian sel saraf otak fisiologis (apoptosis) dan meningkatkan hubungan antar sel saraf otak yang termasuk perubahan morfologis yang dipengaruhi oleh stimulasi secara teratur sehingga bayi saat lahir dapat memiliki sel saraf dan sinap yang lebih banyak dibanding yang tidak mendapatkan pengkayaan (Campbell, 2011;Giselle, 2001;Hermanto, 2001;Hill, 2013 Gambar diatas menunjukkan rerata indeks apoptosis kelompok musik Mozart lebih rendah dari kelompok tidak dipapar musik (0,7 ± 0,41 Vs 1,63 ± 0,82), kelompok musik Mozart lebih rendah dari kelompok musik Beethoven Chopin (0,7 ± 0,41 Vs 1,17 ± 0,68) dan kelompok musik Mozart lebih rendah dari kelompok musik Chopin (0,7 ± 0,41 Vs 1,57 ± 0,49). (Verrusio, et al, 2015).…”

Section: Upaya Peningkatanunclassified

PERBEDAAN PENGARUH PAPARAN MUSIK MOZART, BEETHOVEN, DAN CHOPIN SELAMA KEBUNTINGAN TERHADAP INDEKS APOPTOSIS SEL NEURON DI CEREBELLUM Rattus norvegicus BARU LAHIR

Fajrin

2019

JOB

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The efforts that can be done to improve brain cells in the prenatal period is the provision of nutrients and good stimulation. Exposure to classical music such as Mozart, Beethoven, and Chopin music can increase the wave of brain activity. During pregnancy, Mozart music is proven to decrease the apoptosis of neuronal. Analyzing the difference of apoptosis neuronal of cerebrum and cerebellum of newborn baby of Rattus norvegicus that are exposed to the Mozart, Beethoven, and Chopin music, and that is not exposed to music during pregnancy. Laboratory experimental research, posttestonly control group design. Subjects were female pregnant Rattus norvegicus, grouped into 4 random groups: 1 control group and 3 treatments groups; with 6 samples each. Subjects were super ovulated, and 65 dB intensity of music is played for an hour at 20.00-21.00 on the subjects on 10th day of pregnancy. On 20th day of pregnancy, the mothers was dissected using SC technique. 2 heaviest newborn babies of Rattus norvegicus were taken. Statistical test concluded there was significant differences of apoptosis neuronal of cerebellum of newborn babies of Rattus norvegicus among the exposure to Mozart, Beethoven, and Chopin music, and without the exposure to music with value of p=0,033 in cerebellum. In conclution, the exposure of Mozart’s music during pregnancy perform expression of BDNF cerebellum in the offspring-rat was higher than exposed Beethoven’s music, Chopin and not exposed to music.

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“…It could be that the neurophysiological mechanisms of cognitively intact individuals are different from those of individuals with MCI. Although Mozart's music may affect the activity of cerebral areas involved in the solution of spatial–temporal tasks in cognitively intact individuals, the ME in individuals with MCI could emphasize neuroplastic compensatory mechanisms at the initial stage of cognitive deterioration, with positive effects in terms of spatial–temporal abilities.…”

Section: Second Session—beethovenmentioning

confidence: 99%