Single-site, intensive, community-based blood pressure (BP) intervention programs have led to BP improvements. The authors examined the American Heart Association's Check. Change. Control. (CCC) program (4069 patients/18 cities) to determine whether BP interventions can effectively be scaled to multiple communities, using a simplified template and local customization. Effectiveness was evaluated at each site via site percent enrollment goals, participant engagement, and BP change from first to last measurement. High-enrolling sites frequently recruited at senior residential institutions and service organizations held hypertension management classes and utilized established and new community partners. High-engagement sites regularly held hypertension education classes and followed up with participants. Top-performing sites commonly distributed BP cuffs, checked BP at engagement activities, and trained volunteers. CCC demonstrated that simplified community-based hypertension intervention programs may lead to BP improvements, but there was high outcomes variability among programs. Several factors were associated with BP improvement that may guide future program development. Pivotal to this goal is the development of prevention strategies that are simple, cost-effective, sustainable, and scalable.The AHA has recently supported two large-scale, multifaceted, quality improvement efforts designed to assess the impact of pharmacists and/or community health workers, as well as the signature Heart360 information health technology, on lowering people's blood pressure (BP).3,4 Both of these academic-community partnership initiatives were effective; however, they were also resource-intensive in terms of cost and staffing, raising the question of whether such programs could be effective and scalable with less academic and financial support. Furthermore, it was unclear whether the findings from these initiatives could be generalized to other regions of the United States.