The nano era in dentistry

Abstract

Nanotechnology is a new transnational and transcultural development that is growing rapidly and pervasively. The potential impact of novel Nanodentistry Applications in disease diagnosis, therapy and prevention is foreseen to change oral health care in a fundamental way. This review presents a general overview of the novel nanomaterial and relevant advances of nanotechnology, focusing on promising dental applications. In particular, relevant applications are reported in Restorative dentistry, minimally invasive dental procedures, cancer diagnosis and treatment, molecular imaging and implant dentistry. Many applications are still in their infancy. An increasing number of products are currently under clinical investigation while some are commercially available.

Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages

“…Nanoscale particles are one of the fastest growing sectors in materials research and are currently being used in a wide range of fields, such as industrial, military, and biomedical d e n t a l m a t e r i a l s x x x ( 2 0 1 5 ) xxx-xxx dental applications, numerous new dental products containing nanoparticles have been developed and are available for implants, pulp capping agents, restorative materials, toothpaste, and oral hygiene products [1]. Titanium dioxide, silicon dioxide, aluminum oxide, and zinc oxide are commonly available for a variety of applications in dental materials.…”

Use of magnetic nanoparticles as a drug delivery system to improve chlorhexidine antimicrobial activity

“…43 To data, several nanomaterials such as metallic (silver, zinc oxide) and polymeric (mesoporous silica, polyethylenimine) have been used for dental composite or dental adhesive creation to inhibit pathogen growth. This is due to the generation of reactive oxygen species, disruption of the cell membrane, inhibition metabolic processes, displacement of magnesium ions required for the enzymatic activity of oral biofilms, disturbance of the electron transportation, oxidation of macromolecules and prevention of DNA replication.…”

Nanodentistry: The benefits of nanotechnology in dentistry and its impact on oral health

“…Multi-functionality is the key advantage of nanoparticles over traditional approaches, this attribute includes targeting specific molecular imaging (Mantri and Mantri, 2013). These particles have highly favorable optical and chemical properties for biomedical imaging and therapeutic applications (Gupta et al 2013).…”