The National Institutes of Health measure of Healing Experience of All Life Stressors (NIH-HEALS): Factor analysis and validation

Ameli, Rezvan; Sinaii, Ninet; Luna, María José; Cheringal, Julia; Gril, Brunilde; Berger, Ann

doi:10.1371/journal.pone.0207820

Cited by 23 publications

(33 citation statements)

References 70 publications

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“…7,8 Notably, the results of LTCs expanded beyond the circumstances of the illness and positively impacted other difficult life situations such as divorce or career change. 7,8 These LTCs are hypothesized to comprise the process of psycho-social-spiritual healing 9 and are similar to other concepts described in the literature, such as posttraumatic growth and benefit finding. [10][11][12] Gender is an important factor in psychosocial and spiritual distress and well-being in patient populations.…”

Section: Introductionmentioning

confidence: 72%

“…This questionnaire has strong internal consistency (Cronbach's a = 0.89) and stable factor structure, and its convergent and divergent validity have been confirmed. 9 Factor analysis of the NIH-HEALS supported a three-factor structure, that is, Connection, Reflection & Introspection, and Trust & Acceptance.…”

Section: Questionnairesmentioning

confidence: 93%

“…A full description of the study has been detailed elsewhere. 9 Two hundred patients were recruited from the NIH Clinical Center inpatient and outpatient clinics. These patients were already involved in other clinical trials and research protocols for the treatment of serious, life-limiting medical illnesses.…”

Section: Participants and Proceduresmentioning

confidence: 99%

“…Ameli et al, 9 describe the battery of questionnaires administered to patients in detail. The data collected from the demographics questionnaire and NIH-HEALS were used in the present study.…”

Section: Questionnairesmentioning

confidence: 99%

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Gender Differences in Psycho-Social-Spiritual Healing

Luna

Ameli

Sinaii

et al. 2019

Journal of Women's Health

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Background: Many individuals exhibit significant distress in response to serious and/or life-limiting illness. However, there are others who make life-transforming changes, which involve healing experiences in the psychological, social, and spiritual domains of life regardless of illness outcome. The aim of the present study is to determine if there are any differences in psycho-social-spiritual healing between genders. Materials and Methods: The NIH Healing Experiences in All Life Stressors (NIH-HEALS), a 35-item measure of psycho-social-spiritual healing, is composed of three factors: Connection, Reflection & Introspection, and Trust & Acceptance. NIH-HEALS and a demographic questionnaire were administered to 193 patients with serious and/or life-limiting illness at the National Institutes of Health Clinical Center. Results: In response to NIH-HEALS, men and women significantly differed on the Reflection & Introspection factor. Women reported increased enjoyment of mind-body practices (p < 0.001), compassion (p = 0.005), gratitude (p = 0.014), and a desire to be more positive (p = 0.044) compared to men. Men rated their pain levels (p = 0.035) and severity of illness (p = 0.016) higher and their overall level of health (p = 0.010) poorer compared to women. Women's responses to items regarding compassion (r s = 0.37, p < 0.001) and gratitude (r s = 0.24, p = 0.015) correlated positively with better overall health ratings. Conclusion: Men and women show some differences in their self-reported psycho-social-spiritual healing, which may have implications when designing interventions aimed at promoting a healing experience in the context of serious and life-limiting illness.

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Section: Introductionmentioning

confidence: 72%

Section: Questionnairesmentioning

confidence: 93%

Section: Participants and Proceduresmentioning

confidence: 99%

Section: Questionnairesmentioning

confidence: 99%

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Gender Differences in Psycho-Social-Spiritual Healing

Luna

Ameli

Sinaii

et al. 2019

Journal of Women's Health

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“…Religion refers to a person's faith‐based beliefs and subsequent religious practices. While spirituality can involve religious practices, it is more extensive (Yazgan & Demir, ) and involves constructs such as Connection to a higher power and social connection to friends and family, Reflection and Introspection , including finding meaning in activities, nature and art, and Trust and Acceptance – which involves accepting what is (Ameli et al, ). Academics are still divided over how these two constructs should be defined.…”

Section: Introductionmentioning

confidence: 99%

An Australian study on the benefits of pastoral care to aged care residents in Christian affiliated homes

Gordon¹,

Jones²,

Taylor³

et al. 2019

Health Soc Care Community

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This study aimed to understand the experience of pastoral care (PC), that is, the provision of support, comfort and spiritual counselling, from the perspective of Australian aged care residents. A survey research design captured feedback on participants' PC experience. Outcomes were reported by 575 residents (aged 53-102) across 41 sites.The majority perceived that they received a high quality of care (92%) and benefited from their meeting with the pastoral practitioner (80%), 'often' or 'all of the time'.A few significant differences were found based on participants' gender, spirituality (i.e. connection and meaning), religiosity (i.e. faith beliefs and religious practices) and well-being. Females and participants who identified as both religious and spiritual were more likely to feel that their faiths/beliefs were valued. Those with greater psychological well-being, as defined by the World Health Organisation (1998), were more likely to report receiving a high quality of care and greater benefits from receiving PC than those with poorer well-being. Three overarching themes and eight subthemes were identified from the open-ended responses: 1) personal qualities of the pastoral practitioner; caring, supportive, understanding and empathetic; 2) pastoral practitioner met specific needs; spiritual and religious, friendship and company and assistance, advice and help; and 3) positive impact on the participant; feeling listened to, peaceful and valued, accepted and respected. The qualitative findings resonate with Maslow's Hierarchy of Needs, to feel safe, belong and have self-esteem.There was a synergy between what participants desire in the care they receive, asexpressed in the open-ended questions, and what the pastoral practitioners provide, as indicated in the quantitative findings. A study strength was its mixed-method, multi-site and cross-organisational context, enabling PC to be explored across a diverse sample. Future research should consider a pre-and post-test survey to more comprehensively capture the impact and benefits of PC. K E Y W O R D Saged care, chaplaincy, pastoral care, spiritual care | 367 GORDON et al.

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Psilocybin‐assisted group therapy in patients with cancer diagnosed with a major depressive disorder

Agrawal,

Richards,

Beaussant

et al. 2023

Cancer

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BackgroundDepression is common in patients with cancer and is associated with lower treatment adherence and reduced quality of life. Antidepressants and psychotherapy have limited success in improving depression among patients with cancer. This study explored the safety, feasibility, and efficacy of psilocybin‐assisted therapy in patients with cancer and major depressive disorder.MethodsThis phase 2, open‐label trial enrolled patients with curable and noncurable cancer and major depressive disorder at a single community oncology practice site. A single 25‐mg dose of psilocybin was administered simultaneously to cohorts of three to four participants with individual (4.25 hours in 1:1 therapist‐to‐patient ratio) and group therapeutic support (3.75 hours) before, during, and after psilocybin administration. Outcomes included depression severity, anxiety, pain, demoralization, and disability.ResultsThirty participants completed the study. No psilocybin‐related serious adverse events occurred; treatment‐related adverse events (e.g., nausea, headache) were generally mild and expected. There were no laboratory or electrocardiogram abnormalities. No suicidality was reported. Efficacy was suggested with a robust reduction in depression severity scores from baseline to posttreatment of 19.1 points (95% CI, 22.3 to –16.0; p < .0001) by week 8. Eighty percent of participants demonstrated a sustained response to psilocybin treatment; 50% showed full remission of depressive symptoms at week 1, which was sustained for 8 weeks.ConclusionsPsilocybin‐assisted therapy in group cohort administration was safe and feasible in patients with cancer and depression. Efficacy was suggested based on clinically meaningful reductions in depressive symptoms. The novel, group‐oriented format, compact delivery time, community cancer center setting, and one‐to‐one therapist‐to‐patient ratio could also add to therapeutic gains and efficiency of administration.Trial RegistrationNCT04593563.Plain Language Summary Depression is common in patients with cancer and associated with lower treatment adherence, reduced quality of life, and limited response to antidepressants and psychotherapy. We conducted a phase 2 trial to study a single dose of psilocybin administered in a group therapy setting with one‐to‐one therapist‐to‐participant psychological support to patients with curable and noncurable cancer and major depressive disorder. Findings of the study showed safety (no treatment‐related serious adverse events or suicidality) with psilocybin and suggested efficacy, with a significant reduction in depression severity scores from baseline to posttreatment. Further investigation is warranted.

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The National Institutes of Health measure of Healing Experience of All Life Stressors (NIH-HEALS): Factor analysis and validation

Cited by 23 publications

References 70 publications

Gender Differences in Psycho-Social-Spiritual Healing

Gender Differences in Psycho-Social-Spiritual Healing

An Australian study on the benefits of pastoral care to aged care residents in Christian affiliated homes

Psilocybin‐assisted group therapy in patients with cancer diagnosed with a major depressive disorder

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