The New Doctrine of Acute Pneumonia-the Key to Solve the Problem

Abstract

Pneumonia was described 2,500 years ago by Hippocrates, the father of medicine [1]. However, acute pneumonia (AP) remain an unresolved problem of modern medicine. A lot of money and effort is expended on solving problem of AP. In this connection, it is recalled that World Health Organization has spent 39 billions of dollars in 2010-2015 years to solve this problem [2]. And where are the results?The evaluation of the current situation in this section of clinical medicine looks hopeless, and her improvement is very uncertain.Pneumonia is a leading cause of hospitalization among children in the United States, with medical costs estimated at almost $1 billion in 2009. Despite this large burden of disease, critical gaps remain in our knowledge about pneumonia in children [3].Pediatric pleural empyema has increased substantially over the past 20 years and reasons for this rise remain not fully explained [4].

COVID-19 Pandemic: The Causative Agent is New, the Problem is Old

“…These biological rules have worked and continue to determine the dynamics of the inflammatory process in the lungs, regardless of our perception. The importance of this information for the selection and justification of effective medical care for patients with AP has been proven on the basis of clinical application [25]. A detailed description of the materials of this work is now more important than at the time of its implementation, since over the past period this problem has become much more acute and has become an undoubted super-task for medicine.…”

Let’s evaluate the pandemic in terms of facts, not impressions

“…Today, these materials are published in 9 languages. 40 At a time when antibiotics were unquestionably considered the basis of treatment and a panacea for many diseases, to declare them an auxiliary treatment for AP was a very responsible step. Today, the coronavirus pandemic has changed the conditions for choosing treatment exactly the opposite.…”

The new doctrine is the future solution to the problems of acute pneumonia

“…And no one is confused by the fact that the same forms of antibiotics are used in parallel in the treatment of inflammatory diseases, which are fundamentally different from АP on localization and mechanisms of development.If this principle of treatment has produced the expected results,the discussion of this topic would not be required. Therefore, the published results show not only the negative dynamics of development of purulent complications of the AP, but also the lack of promising strategies to address this problem [1][2][3][4]. "Pediatric pleural empyema has increased substantially over the past 20 years and reasons for this rise remain not fully explained " [5].…”