“…Depressed clients are more likely to benefit from antidepressant medications if they present with the depressive symptoms of early morning awakenings, decreased interest in life activities, loss of appetite, decreased energy, and feelings of guilt (Nelson, Mazure, Quinlan, & Jatlow, 1984). Additionally, clients with endogenous depression have been found to respond well to electroconvulsive therapy (Carney, 1986;Fowles & Gersh, 1979), and those who have bipolar depression or major depression with psychotic features are best treated pharmacologically.…”