The Nucleated Thrombocytoid Cells. I. Electron Microscopic Studies on Chicken Blood Cells

Janzarik, H.; Morgenstern, Eberhard

doi:10.1055/s-0038-1646814

Cited by 10 publications

(2 citation statements)

References 25 publications

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“…Their perinuclear area, encircled by closely spaced microtubules, contains actin-like filaments and a smooth endoplasmic reticulum is sparsely distributed throughout the peripheral cytoplasm (Wood and Ebanks, 1984). Round thrombocytes in birds are similar in shape and size to lymphocytes (Janzarik and Morgenstern, 1979), as in the case of the round thrombocytes of fish Esteban et al, 2000). The cytoplasm of the "spindle cells," a name often used to designate avian oval thrombocytes, frequently appears disrupted in blood smears and show one or more electron-dense, large bodies consisting of an aggregate of numerous small granules (Kumura et al, 1970).…”

Section: Thrombocytesmentioning

confidence: 97%

Are thrombocytes and platelets true phagocytes?

Meseguer¹,

Esteban²,

Rodrı́guez³

2002

Microscopy Res & Technique

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Thrombocytes and platelets, beyond their primary function in hemostasis, seem to play an active role in inflammation. As regards their phagocytic ability, the results to date are confusing, incomplete, and somewhat contradictory. Whereas the interaction of avian thrombocytes or mammalian platelets with bacteria both in vitro and in vivo has received wide attention, almost no information exists on the topic in "lower" vertebrates. The aim of this work is to review the available information on the phagocytic properties of thrombocytes and platelets. Particular attention is payed to the ontogeny of these cells, the soluble factors involved in the inflammatory process derived from them, and their interaction with particulate material, mainly with bacteria.

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Section: Thrombocytesmentioning

confidence: 97%

Are thrombocytes and platelets true phagocytes?

Meseguer¹,

Esteban²,

Rodrı́guez³

2002

Microscopy Res & Technique

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“…Furthermore, estrogens have been described to modulate the immune response in reptiles [25] and mammals [7]; we have looked for different patterns of response depending on the serum levels of 17b-estradiol (E 2 ). Another main factor acting on the immune response and lymphoid distribution is the age since it is well known that young birds have different patterns of lymphoid distribution than adults [12,17]. Therefore, we have studied the response of juveniles versus adults searching for different patterns of response depending on the age of the animal.…”

Section: Introductionmentioning

confidence: 99%

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Muñoz

Fuente

2003

Pflugers Arch - Eur J Physiol

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The immune function of wild birds is practically unknown. We have studied several functions of splenic leukocytes from the gull Larus ridibundus. Considering that avian physiology is strikingly affected by the seasonal migratory cycle, those functions were analyzed throughout the seasonal cycle. The functions assayed were: adherence to substrate, chemotaxis and lymphoproliferative response to mitogens. Estrogens have been reported to modulate the immune response in mammals; therefore serum levels of 17beta-estradiol were measured in order to find a putative effect of this hormone on the immune response of female gulls. According to our results, gull splenic leukocytes showed a response similar to that reported in mammals and poultry. In regard to the effect of the seasonal migratory cycle, when the gulls arrived from the migratory flight they showed an immunosuppression as we have obtained in chemotaxis and proliferations assays. The immune response increased during the resting period and especially in the premigratory period. We have found a lack of a direct effect of the age of the animals or even the serum estrogen levels in the immune response of the migratory gulls. These results suggest the existence of other hormones and releasing factors, which would modulate the immune response in gulls, or a unique major effect due to the long flight effort.

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Nucleated thrombocytoid cells

Janzarik

1981

Cell Tissue Res.

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The so-called nucleated thrombocytes of the domestic fowl (and mallard) were analyzed intravitally by use of phase- and interference-contrast microscopy with regard to their morphology and functional state, and in comparison to other avian blood cells and mammalian blood platelets. Since nucleated thrombocytoid cells of birds do not differ in size from white blood cells, they are automatically included in differential cell counts. They can easily be confused with other white blood cells and even with erythrocyte ghosts, which also appear to be hemostatically active elements. However, the nucleated thrombocytoid cells displayed a characteristic, definite morphology. The platelet-like spreading process and elongation of aging cells in vitro to spindle forms deserve special attention. A technique of counting live avian blood cells was used to determine their values in chickens of different sexes and ages.

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The Nucleated Thrombocytoid Cells. I. Electron Microscopic Studies on Chicken Blood Cells

Cited by 10 publications

References 25 publications

Are thrombocytes and platelets true phagocytes?

Are thrombocytes and platelets true phagocytes?

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Nucleated thrombocytoid cells

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