Objectives: We aimed to describe the main psycho-social factors related to obesity in an adult population and to develop a unified construct (psycho-social profiles), in order to explore the associations between socioeconomic characteristics and these psycho-social profiles. Methods: In its second wave, the RECORD Study assessed 6460 participants aged 30-79 years in the Paris region between 2011 and 2014. Factor analyses followed by cluster analysis were applied to identify psycho-social profiles related to obesity. The two psycho-social profiles were: adverse profilenegative body image, underestimation of the impact of weight in quality of life, low weight-related self-efficacy, and weight-related external locus of control; and favorable profile-positive body image, high self-efficacy, and internal locus of control. The relationship between three socioeconomic dimensionscurrent socioeconomic status, childhood socioeconomic status, and neighborhood education status-and psychosocial profiles was assessed through binomial logistic regression adjusted for age, gender, depression, living alone, and weight status. Results: Contrary to hypotheses, there were no associations between socioeconomic characteristics and obesity-related psycho-social profiles after adjustment for body mass index. Depressive symptoms (OR: 2.21, 95% CI: 2.70, 4.04) and being a female (3.31, 95%CI: 2.70, 4.40) were associated with an adverse psycho-social profile. Conclusions: Psycho-social profiles could help to understand the multifactorial nature of the determinants of obesity.