THE OCCURRENCE OF EPISODES OF IMMUNIZATION IN PREGNANCY ASSOCIATED WITH Rh HÆMOLYTIC DISEASE OF THE NEW‐BORN

Ga, Kelsall; Gh, Vos; Kirk, R. L.

doi:10.5694/j.1326-5377.1959.tb59175.x

Cited by 16 publications

(2 citation statements)

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“…The evaluation of Rh antibody titre differences recorded in the first trimester of pregnancy and before delivery would then indicate the intensity of R h immunization for that pregnancy. This method of assessing sensitization by the Rh factor was used in a previous study from this laboratory by KELSALL and VOS [2].…”

Section: Methodsmentioning

confidence: 99%

The Effect of External Version on Antenatal Immunization by the Rh Factor

Vos

1967

Vox Sanguinis

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Summary The present study has shown that the routine practise of antenatal manipulations such as external version is associated with a significant increase in the frequency of episodes of Rh immunization not only among Rh negative mothers who were already immunized before the present pregnancy commenced but also among those not previously immunized. The findings would seem to indicate that the disruption of the placental circulation is enhanced by such procedures and the ultimate risk involved in intensifying the haemolytic process ‘in utero’ can therefore not be ignored.

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Section: Methodsmentioning

confidence: 99%

The Effect of External Version on Antenatal Immunization by the Rh Factor

Vos

1967

Vox Sanguinis

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“…Stratton (1955) found incomplete anti-D in a patient's serum 38 years after her last pregnancy. In some instances, the titre of anti-D may fall relatively rapidly after pregnancy; Kelsall, Vos and Kirk (1959) reported a fall in the indirect antiglobulin (IAG) titre of anti-D from 1024 to 16 in a little over 2 years. Ward (1957) tested (by saline and polyvinylpyrrolidone techniques) one blood sample from each of 478 immunized women, within 6 years of their last pregnancy.…”

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confidence: 99%

The Decline and Fall of Anti‐Rh(D)

Hopkins

1969

Br J Haematol

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Summary. Among women immunized to the Rh(D) antigen, the titre of anti‐D measured by the indirect anti‐globulin (TAG) technique falls, on average, to half of the original value in 5–7 years after a pregnancy, but there is a wide range of individual variation. This range is specified. The fall is greater when the initial titre was high. The average titre of saline anti‐D activity falls much more rapidly, although in a minority of individuals this class of antibody persists for many years. The saline anti‐D titre of some women may rise following pregnancy.

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Freda¹,

Gorman²

1962

Rhesus Haemolytic Disease

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THE OCCURRENCE OF EPISODES OF IMMUNIZATION IN PREGNANCY ASSOCIATED WITH Rh HÆMOLYTIC DISEASE OF THE NEW‐BORN

Cited by 16 publications

References 5 publications

The Effect of External Version on Antenatal Immunization by the Rh Factor

The Effect of External Version on Antenatal Immunization by the Rh Factor

The Decline and Fall of Anti‐Rh(D)

Current Concepts

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