The Occurrence of Heterozygous Beta–thalassaemia as Screened by Quantitative Haemoglobin Electrophoresis in Pregnancy

Smith, Margery A.; Whiteside, M. G.; Campbell, D. J.

doi:10.5694/j.1326-5377.1971.tb92389.x

Cited by 9 publications

(2 citation statements)

References 9 publications

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“…MSC marker phenotyping was performed using CD14, CD34, CD90, and CD105 antibodies according to an established protocol. 19 , 20 FACS-based analysis of the flow cytometric immunophenotype requires 2 × 10 6 cells per CD marker. Therefore, we obtained 8 × 10 6 of cells for 4 CD markers through culture expansion.…”

Section: Methodsmentioning

confidence: 99%

Arthroscopic Implantation of Adipose-Derived Stromal Vascular Fraction Improves Cartilage Regeneration and Pain Relief in Patients With Knee Osteoarthritis

Kim

Suh

et al. 2023

Arthroscopy, Sports Medicine, and Rehabilitation

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Section: Methodsmentioning

confidence: 99%

Arthroscopic Implantation of Adipose-Derived Stromal Vascular Fraction Improves Cartilage Regeneration and Pain Relief in Patients With Knee Osteoarthritis

Kim

Suh

et al. 2023

Arthroscopy, Sports Medicine, and Rehabilitation

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“…Cells regularly seeded at 50 cells/cm 2 were expanded till reaching the adequate number for analyzing the flow cytometric immunophenotype using fluorescence-activated cell sorting (FACS). MSC marker phenotyping was performed using CD14, CD34, CD90, and CD105 antibodies according to an established protocol [ 9 , 49 ]. For analysis of the flow cytometric immunophenotype using FACS, 2 × 10 6 of cells are required per a CD marker.…”

Section: Methodsmentioning

confidence: 99%

Comparative matched-pair cohort analysis of the short-term clinical outcomes of mesenchymal stem cells versus hyaluronic acid treatments through intra-articular injections for knee osteoarthritis

et al. 2020

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Purpose Intra-articular injection of hyaluronic acid (HA) has shown promises in reducing pain and improving physical function in knee osteoarthritis (OA). Recently, cell-based therapies using mesenchymal stem cells (MSCs) have emerged as potential treatments. However, few studies have compared the treatment outcomes between MSCs and HA. This study aimed to compare the clinical and radiological outcomes of intra-articular injections of MSCs versus HA in patients with knee OA. Methods A cohort of 209 patients with knee OA were retrospectively screened for those who underwent intra-articular injections using MSCs or HA. Thirty MSC-treated patients (MSC group) were pair-matched with thirty HA-treated patients (HA group) based on gender and age. Clinical outcomes were evaluated using the visual analog scale (VAS), International Knee Documentation Committee (IKDC) rating system, and Lysholm scoring system. Radiological evaluation was assessed using the Kellgren-Lawrence (K-L) grading system. Results MSC treatment yielded consistent significant improvements in VAS, IKDC and Lysholm scores. In the HA group, VAS scores significantly decreased at 1 month, slightly increased at 3 months, and increased significantly from 3 months to 1 year after injection. The IKDC and Lysholm scores improved significantly until 3 months, but gradually worsened thereafter. Significantly greater improvements in VAS (P = 0.041), IKDC (P = 0.014), and Lysholm (P = 0.020) scores were observed in the MSC group compared to those in the HA group at 1-year post-treatment. The K-L grade worsened in a few patients, especially those in the HA group, albeit no significant difference. Conclusions MSC group showed better VAS, IKDC, and Lysholm scores at 1-year post-treatment, compared to the HA group, although earlier clinical improvements were superior in the HA group for the initial 3 months. Level of Evidence Therapeutic study, Level III.

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Clinical &Amp; Laboratory Haematology

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The Occurrence of Heterozygous Beta–thalassaemia as Screened by Quantitative Haemoglobin Electrophoresis in Pregnancy

Cited by 9 publications

References 9 publications

Arthroscopic Implantation of Adipose-Derived Stromal Vascular Fraction Improves Cartilage Regeneration and Pain Relief in Patients With Knee Osteoarthritis

Arthroscopic Implantation of Adipose-Derived Stromal Vascular Fraction Improves Cartilage Regeneration and Pain Relief in Patients With Knee Osteoarthritis

Comparative matched-pair cohort analysis of the short-term clinical outcomes of mesenchymal stem cells versus hyaluronic acid treatments through intra-articular injections for knee osteoarthritis

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