The Occurrence of Mycoplasmas in the Urinary Tract of Patients With Chronic Pyelonephritis

Thomsen, A. C.

doi:10.1111/j.1699-0463.1975.tb00063.x

Cited by 13 publications

(12 citation statements)

References 7 publications

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“…This was simillar to other previous reports (Thomsen, 1978a;1978b;Thomsen and Lindskov, 1979). It might be due to the high sensitivity of mycoplasma (pH, temperature and materials present in culture media and clinical specimens; (Humburg et al, 2011) as well as a loss of viability during specimen collection and/or transport, furthermore, mycoplasma antibody response is one of the criteria for diagnosing the disease and antibiotic inhibition is sometimes difficult to determine (Taylor-Robinson,1996a;Amirmozafari et al, 2009;Abdul-Wahab, 2010;Abdul-Wahab and Al Sunaidi, 2013), Further research studies are needed for rapid detection of the Mycoplasma hominis in patients with the urinary tract diseases using other diagnostic method such as PCR assay that was described as rapid altrinatives to culture for the detection of of M. hominis and Ureaplasma species (Cunningham et al, 2013).…”

Section: Discussionsupporting

confidence: 76%

“…The prevalence of Mycoplasmas in women with lower uriary tract symptoms (30.3%) was statistically significant and higher than in the group without lower urinary symptoms (14.5%) (p = 0.011). A study conducted by (Thomsen, 1978a;1978b) resulted in Mycoplasma hominis being detected from the upper uriary tract in 7 out of a group of 80 infected patients with acute pyelonephritis and from 0 of 60 of the control patients group with noninfectious diseases of the urinary tract. On comparing the infected and control groups, the result was found to be statistically significant.…”

Section: Discussionmentioning

confidence: 99%

“…However, there are other studies reported that Mycoplasma hominis as one of the agent that is believed to be associated with urinary tract infections (Thomsen, 1978a;1978b;Sai-Yin and Kwok-Yung, 1995;Satoshi et al, 2006;Totten et al, 2008;Taylor-Robinson and Furr, 2010;Humburg et al, 2011) .This pathogen has been recognized as potentially genital mycoplasma species; it is associated with various infectious diseases in adult men and woman. The organism could cause pyelonephritis, pelvic inflammatory disease, postpartum and postabortion fever in addition to extragenital diseases including septicemia, joint infections, central nervous system infections, respiratory tract infections and wound infections particularly after surgery (Thomsen and Lindskov, 1979;Taylor-Robinson, 1996a;1996b;Stellrecht et al, 2004;Waites et al, 2005;Totten et al, 2008;Patel and Nyirjesy, 2010;Taylor-Robinson and Furr, 2010;Taylor-Robinson and Jensen, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…In newborn children, this pathogen can also can cause meningitis, pneumonia and abcess (Pereyre et al, 2009). The organism been been recovered from the upper urinary tract in patients with acute pyelonephritis (Thomsen, 1978a;1978b;Sai-Yin and Kwok-Yung, 1995), women with lower urinary tract (Humburg et al, 2011). It has also been recovered from the urine of asymptomatic patients (Satoshi et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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DETECTION OF <i>MYCOPLASMA HOMINIS</i> IN PATIENTS WITH URINARY TRACT INFECTIONS

Abdul-Wahab¹

2014

American Journal of Infectious Diseases

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Mycoplasma hominis is one of the well known genital mycoplasma agent that has been recognized as potentially pathogenic species and associated with various infectious diseases in adult men and woman. The organism could cause pelvic inflammatory disease, postpartum, postabortion fever and pyelonephritis. The Aim of this prospective study was to detemine the occurrence and prevalence of Mycoplasma hominis in patients with urinary tract infections, since they are usually not detected by routine microbiological examination of urine samples in laboratory department. For this purpose, Culture method was to be attempted as the current laboratory methods of choice for detection urogenital mycoplasmas infections. This study was designed as a case-control study in which a total of 100 patients with mean age of the of 42.78±22.49 (95% CI = 39-49.17) in case group as well as a mean age of 48.18±18.81 ((95% CI = 42.83-53.53) in the control group. The patients of both sexes were investigated for the presence of M. hominis and they were admitted to the urology department at asser central hospital in Abha (a city in southwest region of Saudi Arabia), during over a period of one year (February, 2013-March, 2014. A detailed history with specific urinary symptoms and signs was obtained as a result. These patients were divided into two groups: The first group (or case group) and the second group (or control group): The case group, included 50 symptomatic patients who had been admitted in hospital and they were examined for the presence of one or more of the following specific urinary symptoms and signs: Urinary frequency, dysuria, suprapubic/pelvic pain. Unlike the case group, the control group included 50 asymptomatic patients who were free of any specific urinary symptoms and they were matched by the first group for their age index. First voided urine specimens were tested using urine microscopy, culture for M hominis was performed and the isolates were identified serologically by growth inhibition test (disc method). In the case group, 8 cases out of 50 and in control group 1 out 50 were positive for M. hominis infection. The incidence of M. hominis was higher and statistically significant among case symptomatic patients group (8/50, 16%) than control asymptomatic patients group patients (1/50, 2%). On applying tests of significance to the observed data for isolation of Mycolplasma hominis among cases and controls, the values were found to statistically significant. Chisquare test with Yate's correction [χ AJIDArabia. Infection caused by M hominis was associated with higher incidence rate in patients with symptomatic urinary tract diseases. Further work studies is needed for their rapid detection of these organism in urine samples using other diagnostic methods such as PCR. Further knowledge of the role and the effect of this pathogen in patients with urinary tract infections can be a prospective field of study.

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Section: Discussionsupporting

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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DETECTION OF <i>MYCOPLASMA HOMINIS</i> IN PATIENTS WITH URINARY TRACT INFECTIONS

Abdul-Wahab¹

2014

American Journal of Infectious Diseases

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“…Whereas the mycoplasmal flora of the human urethra and bladder has been the subject of numerous investigations (3, 7, 8, 10,15,17) only a few studies of the occurrence of mycoplasmas in the upper urinary tract have been reported (11, 16,17).…”

mentioning

confidence: 99%

THE ISOLATION OF MYCOPLASMA PRIMATUM DURING AN AUTOPSY STUDY OF THE MYCOPLASMA FLORA OF THE HUMAN URINARY TRACT

Thomsen¹

1974

Acta Pathologica Microbiologica Scandinavica Section B Microbio

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The mycoplasmal flora of the urinary tract of 19 men and 21 women was investigated at autopsy. Mycoplasmas were isolated from the urethra of 9 bodies. One of the isolates was identified biochemically and serologically as M. primatum. This is the second isolation from man of this simian mycoplasma species. Three of the remaining isolates from the urethra were identified as M. hominis, one as M. fermentans and four as U. urealyticum. U. urealyticum was isolated twice from the bladder urine. In one case, a strain of U. urealyticum was isolated from the cortex of a kidney with histologically demonstrable non‐specific inflammation.

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Concrement formation in the urinary bladder in rats inoculated with Ureaplasma urealyticum

et al. 1985

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To study the concrement-forming ability of Ureaplasma urealyticum in the urinary tract, viable and heat-killed ureaplasmas as well as urease and non-urease-producing bacteria were inoculated into the bladder in rats. Viable ureaplasmas, in contrast to heat-killed, caused the formation of bladder stones with a frequency corresponding to urease-producing bacteria (Proteus mirabilis). It was not possible to reculture the inoculated ureaplasmas from the urinary tract. Non-urease producing microorganisms (Escherichia coli and Mycoplasma hominis) only occasionally induced stone formation. The results indicate that U. urealyticum can initiate stone formation, a property that appears to be associated with the urease activity of the organism.

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The Occurrence of Mycoplasmas in the Urinary Tract of Patients With Chronic Pyelonephritis

Cited by 13 publications

References 7 publications

DETECTION OF <i>MYCOPLASMA HOMINIS</i> IN PATIENTS WITH URINARY TRACT INFECTIONS

DETECTION OF <i>MYCOPLASMA HOMINIS</i> IN PATIENTS WITH URINARY TRACT INFECTIONS

THE ISOLATION OF MYCOPLASMA PRIMATUM DURING AN AUTOPSY STUDY OF THE MYCOPLASMA FLORA OF THE HUMAN URINARY TRACT

Concrement formation in the urinary bladder in rats inoculated with Ureaplasma urealyticum

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