The Ocular Effects of Gases When Injected Into the Anterior Chamber of Rabbit Eyes

Lee, D A; Wilson, M. Roy; Yoshizumi, Marc O.; Hall, Michael O.

doi:10.1001/archopht.1991.01080040139045

Cited by 75 publications

(41 citation statements)

References 10 publications

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“…However, their use has to be limited strictly to the posterior segment of the eye because corneal toxicity has been reported for perfluorooctane, perfluoropolyether [15] and perfluoro- phenanthrene [16]. Similar observations have been described after aqueous replacement with silicone oil or gas [12,19].…”

Section: Discussionmentioning

confidence: 90%

Anterior segment changes in rabbits after experimental aqueous replacement with various amounts of different perfluorocarbon liquids

Stolba

Krepler

Velikay

et al. 1999

Graefe's Archive for Clinical and Experimental Ophthalmology

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Section: Discussionmentioning

confidence: 90%

Anterior segment changes in rabbits after experimental aqueous replacement with various amounts of different perfluorocarbon liquids

Stolba

Krepler

Velikay

et al. 1999

Graefe's Archive for Clinical and Experimental Ophthalmology

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“…26 Ayrıca intrakamaral gaz enjeksiyonunun konsantrasyonlarının dilüe edilerek kullanılması, deneysel olarak gösterilmiş olan korneal endotelyal toksisiteyi azaltmak adına da anlam taşımaktadır. 27,28 Olgumuzda yeterli genişlikteki Descemet apozisyonu sağlanacak gaz, enjeksiyondan sonra daha fazla genleşmenin beklenmediği C3F8 konsantrasyonu olan %10'luk oranla sağlanmıştır.…”

Section: Discussionunclassified

Katarakt Ameliyatı Sonrası Akut Kornea Ödeminin Bir Nedeni: Descemet Membran Dekolmanı Ayırıcı Tanısı ve Tedavisi

Selver¹,

Eğrilmez²

2014

tjo

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Olağan seyirle tamamlanmış fakoemülsifikasyon cerrahisi sonrası akut kornea ödemi gelişen bir katarakt olgusunda, Descemet membran dekolmanının ayırıcı tanı ve etkin tedavisini sunmak. Yetmiş iki yaşında kadın hasta, sağ gözde 12 gün önce geçirilmiş olağan seyirli bir fakoemülsifikasyon cerrahisi sonrası postoperatif halen devam eden yoğun kornea ödemi ve görme bozukluğu ile kliniğimize refere edildi. Hastanın görme keskinliği sağ gözde 2 metreden parmak sayma, sol gözde 0,4 düzeyindeydi. Biyomikroskopik muayenede sağ gözde santralde ve medialde daha belirgin olmak üzere yaygın kornea ödemi izlenmekteydi. Sol gözde nükleer skleroz mevcuttu. Göz içi basınçları her iki gözde normaldi. Sistemik sorgusunda arteriyel hipertansiyon öyküsü mevcuttu. Hastaya slit aydınlatma ile tüm kornea alanı taranarak yapılan dikkatli muayene ile medialdeki yan giriş yakınında saptanan Descemet membran dekolmanı ve buna bağlı kornea ödemi tanısı konarak, ön kamaraya perfloropropan (C3F8) enjeksiyonu yapıldı. Enjeksiyonu takip eden 3. günde, kornea endotelinde parasantral Descemet kırışıklıkları dışında kornea saydamdı, sağ gözde görme keskinliği 0,5 düzeyine çıktı. (Turk J Ophthalmol 2014; 44: 486-9) Anah tar Ke li me ler: Descemet membran dekolmanı, korneal ödem, ön kamaraya perfloropropan (C3F8) gaz enjeksiyonu To report the diagnosis and effective treatment of corneal edema due to Descemet's membrane detachment following uneventfully completed phacoemulsification surgery in a case. A 72-year-old female patient was referred to our clinic with a continuing gradual deterioration of vision and diffuse corneal edema in her right eye, 12 days after an uneventful phacoemulsification surgery. Her visual acuity was counting fingers from 2 meters in the right eye and 0.4 in the left eye. Slit lamp examination revealed a corneal edema mostly prominent at the central and medial cornea with a Descemet's membrane detachment near the medial site port area in the right eye. There was a mild nuclear cataract in the left eye. Intraocular pressures were normal in both eyes. The patient had a medical history of arterial hypertension. Descemet's membrane detachment which was close to the medial side port area was detected on a detailed slit lamp examination, and anterior chamber tamponade was performed with perfluoropropane (C3F8) under topical anesthesia. At the third postoperative day, her right eye was comfortable, the corneal epithelial edema had almost cleared, and the Descemet's membrane appeared to be reattached completely with only small wrinkles remaining. Her visual acuity improved to 0.5 in the right eye. (Turk J Ophthalmol 2014; 44: 486-9) Key Words: Descemet's membrane detachment, corneal edema, anterior chamber tamponade with perfluoropropane (C3F8) Özet Summary GirişLiteratürde ilk kez sistematik olarak 1928 yılında Samuels 1 tarafından tanımlanan Descemet membran dekolmanı, katarakt operasyonunu da içine alan çok sayıda oküler cerrahi uygulamasından sonra ortaya çıkabilen bir ön segment patolojisidir. [1][2][3][4][5][6] Dar ön kamara, ...

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“…[16][17][18][19] The toxic effects of C 3 F 8 gas on the corneal endothelium are well documented in the literature. 1,[11][12][13] reported that the corneal endothelial damage associated with pars plana vitrectomy and total lensectomy and C 3 F 8 gas tamponade is greater than that associated with vitrectomy combined with anterior capsule preserved lensectomy and C 3 F 8 gas tamponade; however, they did not mention the concentration of the C 3 F 8 gas. Lee et al 13 reported that diluted C 3 F 8 gas is no more toxic to corneal endothelium than pure gas, but their study simply compared diluted gas with pure gas.…”

Section: Discussionmentioning

confidence: 99%

“…Some reports have revealed that intraocular gases, including C 3 F 8 , are toxic to the corneal endothelial cells and stroma and induce lens opacities. [1][2][3][4][5][6][7]11,12 Lee et al 13 reported that diluted C 3 F 8 gas (15%) does not damage corneal endothelial cells, whereas pure C 3 F 8 gas does. However, they focused on a simple comparison between effects of diluted and pure C 3 F 8 gas on the cornea, but generated no data for different concentrations of C 3 F 8 gas.…”

Section: Introductionmentioning

confidence: 99%

The effect of C3F8 gas on corneal endothelial cells in rabbits

Jee

Kim

2010

Jpn J Ophthalmol

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The Ocular Effects of Gases When Injected Into the Anterior Chamber of Rabbit Eyes

Cited by 75 publications

References 10 publications

Anterior segment changes in rabbits after experimental aqueous replacement with various amounts of different perfluorocarbon liquids

Anterior segment changes in rabbits after experimental aqueous replacement with various amounts of different perfluorocarbon liquids

Katarakt Ameliyatı Sonrası Akut Kornea Ödeminin Bir Nedeni: Descemet Membran Dekolmanı Ayırıcı Tanısı ve Tedavisi

The effect of C3F8 gas on corneal endothelial cells in rabbits

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