The ontogeny of fidgety movements from 4 to 20 weeks post-term age in healthy full-term infants

Ferrari, Fabrizio; Frassoldati, Rossella; Berardi, Alberto; Palma, Francesca Di; Ori, Luca; Lucaccioni, Laura; Bertoncelli, Natascia; Einspieler, Christa

doi:10.1016/j.earlhumdev.2016.10.004

Cited by 38 publications

(34 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…), but the general movement's basic movement melody now consists of a continuous stream of small and elegant movements occurring irregularly over the body . Fidgety movements are most prominently present between 11 weeks and 16 weeks corrected age …”

Section: Typical General Movement Developmentmentioning

confidence: 99%

Neural substrate and clinical significance of general movements: an update

Hadders‐Algra

2017

Develop Med Child Neuro

102

115

View full text Add to dashboard Cite

General movements are present from early fetal life to 3 to 5 months corrected age. Atypical general movements, especially in the last, so‐called fidgety general movement phase, are predictive of cerebral palsy (CP). This review updates knowledge on the neural substrate and clinical significance of typical and atypical general movements. Typical general movements are primarily characterized by complexity and variation. Presumably these core characteristics are initially induced by modulating activity of the cortical subplate. When the subplate gradually dissolves between 3 months before term and 3 months corrected age the cortical plate takes over. This coincides with the fidgety general movement phase. Conceivably, fidgety activity reflects ‘sparsification’, i.e. fragmentation of cortical network activity. The quintessential feature of atypical general movements is reduced complexity and variation. This is attributed to impaired integrity of extensive cortical‐subcortical networks, in which the subplate and periventricular white matter play a prominent role. The most serious forms of network impairment are associated with absent fidgety movements. What this paper adds The emergence of fidgety movements reflects a developmental transition from widespread to fragmented cortical network activity. Atypical general movements characterized by reduced complexity and variation are attributed to impaired integrity of extensive cortical‐subcortical networks.

show abstract

Section: Typical General Movement Developmentmentioning

confidence: 99%

Neural substrate and clinical significance of general movements: an update

Hadders‐Algra

2017

Develop Med Child Neuro

102

115

View full text Add to dashboard Cite

show abstract

“…Prechtl and co-workers demonstrated that GMs in particular are an excellent marker for early brain impairment and dysfunction. [8][9][10][11][12] What are General Movements?…”

Section: Name: Erikmentioning

confidence: 99%

“…Brain lesions affect the quality rather than quantity of GMs, as has been demonstrated by various studies. [8][9][10][11][12] When the CNS is impaired, the GMs lose their main three characters: complexity, variability and fluency. There is only one exception to this rule: severe perinatal asphyxia is accompanied by a transient phase of hypokinesis: i.e.…”

Section: Name: Erikmentioning

confidence: 99%

See 1 more Smart Citation

Volume 10 Issue 2 2017

Ballweg¹

2019

View full text Add to dashboard Cite

M y husband, Jeff, and I are honored to share our story about love, hope, faith, and strength. These four concepts kept us going through some of the hardest and happiest days of our lives. We hope other parents and families find comfort and peace after reading our story. We feel this confirms that miracles do happen, and that even in the most difficult situations, strength and resiliency exist in all of us. Our journey in the Mayo Clinic Newborn Intensive Care Unit (NICU) began after we welcomed our beautiful daughter, Brinley Grace Eveslage, into the world on July 14, 2015 at 12:32 pm. She weighed 5 pounds 11 ounces at 33 weeks gestation. It was a groggy Monday after a busy weekend with a baby shower my awesome sister planned for us. I was uncomfortable after developing lower back pain. I didn't sleep much Sunday night and waddled into work. I planned to go home early and treat myself to a massage. How on earth was I going to survive another seven weeks? My coworkers planned a surprise baby shower so I stuck out the day. What I did not realize was that I was in active labor. I left the clinic, where I work as a medical social worker, to change clothes and to feed the dog, only to return to triage that evening. I was convinced I was not in labor; I did not feel a single contraction but something just felt off. "Surprise, you are dilated to seven. You are having a baby." Tears flowed down my face in fear as I knew it was too soon. I was given medication to try to stop delivery but I threw it up. Contractions progressed quickly and Brinley knew she needed to come out as, unknown to us at the time, her intestine twisted and ruptured before birth. We were blessed with a smooth vaginal delivery. Brinley was swept quickly into another room where the neonatal team patiently waited. They, too, were surprised to see her with a blue and distended tummy. We expected a premature baby who would be healthy. Our world changed as the neonatologist quickly explained she needed exploratory surgery and to be moved to the NICU. We were able to meet her but could not hold her right then. She was beautiful with big eyes and was exploring the sound of our voices. We held her hand and wept with overwhelming emotion. Not Continued on page 2

show abstract

“…Im Alter von 51 -56 WPMA sollten sie auf jeden Fall zu beobachten sein. Ab 60 WPMA werden sie vollständig von der Willkürmotorik abgelöst[43]. FM zeichnen sich durch tänzelnde, elegante Bewegungen mit moderater Geschwindigkeit und geringer Amplitude aus.MerkeBei Läsionen des ZNS kommt es mit hoher Wahrscheinlichkeit zu qualitativen Veränderungen der General Movements.Als "Cramped Synchronized General Movements" (CSGM) werden starre Bewegungen des gesamten Körpers bezeichnet.…”

unclassified