The Organotin Applications in Biological, Industrial and Agricultural Sectors: A Systematic Review

Abstract

In the last few decades, the chemistry of organotin (IV) complexes of many biologically important compounds, has received significant interest in the preparation, identification and application of organotin units which are employed as photo-stabilizers, pesticides, pharmaceuticals and fire retardants. Biological properties of the system are modified by changing the organic ligands in organotin(IV) complexes. Using organotin (IV) materials in medications has brought significant attention by researchers recently. This is due to these compounds have demonstrated an excellent biological activity as well as organotin (IV) compounds are considers as anti-oxidant molecules as they work free radical scavengers. On the other hand, organotin (IV) complexes were used as photo-stabilizers for different types of plastic polymers. In this paper will review the most important potential work using organotin (IV) in both medicine and industrial applications.

Anthracene appended organotin (IV) compounds: Synthesis, structure elucidation and their cytotoxicity against A549 and RBL cancer cell lines

“…Organotin (IV) compounds are known for their interesting structures and diverse applications in industries such as agriculture, medicine, and materials science 1–9 . In the agricultural sector, these compounds have proven highly effective in controlling fungi, bacteria, and viruses that cause diseases in grapes, citrus fruits, and vegetables 1,2 .…”

“…Organotin (IV) compounds are known for their interesting structures and diverse applications in industries such as agriculture, medicine, and materials science. [1][2][3][4][5][6][7][8][9] In the agricultural sector, these compounds have proven highly effective in controlling fungi, bacteria, and viruses that cause diseases in grapes, citrus fruits, and vegetables. 1,2 They also serve as biocides in industrial settings, effectively combating microorganisms that lead to corrosion, fouling, and issues in cooling water systems, as well as in oil and gas production facilities.…”

“…[1][2][3][4][5][6][7][8][9] In the agricultural sector, these compounds have proven highly effective in controlling fungi, bacteria, and viruses that cause diseases in grapes, citrus fruits, and vegetables. 1,2 They also serve as biocides in industrial settings, effectively combating microorganisms that lead to corrosion, fouling, and issues in cooling water systems, as well as in oil and gas production facilities. 10 Organotin (IV) compounds have also shown promising results as potential anticancer agents due to their ability to inhibit cancer cell growth and induce cell death in certain types of cancer.…”

Testing the Activity of the Synthetic Compound Diphenyltin (Iv)n- Benzyl Methyl Dithiocarbamate Against Breast Cancer McF-7

“…Dithiocarbamate compounds can be classified into three main groups, namely primary, secondary and tertiary (8) Dithiocarbamate compounds are very potent compounds in agriculture, industry, and medicine. According to the latest activity of dithiocarbamate compounds, it can be used as an antifungal, anti-bacterial, anti-cancer, anti-alkylation, and apoptotic-inducing activity of the metal dithiocarbamate complex and its mixed ligands (9) This is known based on research that reports that the synthesis results of the compound Dibyltimah (IV) N-Benzilmethylditiokarbamat have been shown to have antifungal activity against the fungus Candida Albicans by 17 mm (dose 0.050 grams) and 16.58 mm (dose 0.050 grams) (10), dithiocarbamate compounds are also very active against Salmonella typhi and E. Coli bacteria with very small doses and have strong activities (11). Many studies of dithiocarbamate compounds have been carried out on anticancer P-388(8), dithiocarbamate compounds have also been found to be active in anticancer leukemia with active human hepatocarcinoma cells with concentrations below 10 μgr / ml (12).…”