The Origin of Immunity by Means of Prior Infection and Vaccination with Implications for the Origin of Species

Abstract

The expectation that vaccines would solve the COVID-19 problem through herd immunity, which followed logical deductions from inflammatory phenomena in which Mechnikov and his contemporaries described immunity as originating from the elimination of pathogens by a system of cells and substances which has since been named the immune system which would prevent onward transmission of the pathogen, has failed to find representation in reality. But upon illustrating the reality in which the immunological phenomena through which immune mechanisms protect us from the pathological manifestations that occur in response to the pathogen, they were found to be brought about by the attenuation of the causative influence of the same pathogen from a prior infection and an entity that is immunologically-linked with the pathogen from vaccination so that the single pathway through which such pathological manifestations are brought in response to these influences are blocked and infection with the pathogen remains asymptomatic for as long as either or both of the conditions that hive rise to different but connected paths to immunity persist. Rather than asymptomatically hosted variants and subvariants to have become masters in the art of escaping the system which we have described as immune for in the absence of knowledge of reality for severe manifestations to occur in both the vaccinated and unvaccinated or to have become more transmissible for surges of COVID-19 hospitalizations and death to occur, it is these protective conditions that give rise to immunity that needs to disappear. And the higher likelihood of one path disappearing in the unvaccinated than both disappearing in the vaccinated explains why the unvaccinated are at greater risk of such unfortunate events. If we will put an end to such deaths which claimed the lives of millions prematurely during this pandemic and prevent those which may decimate our populations if pathological manifestations such as malignancies should appear catastrophically in our species as they did in Tasmanian devils, an understanding of the immunological nature of the pathological effects of the pathogens that are linked with these manifestations, which will enable us to keep both conditions stable in the vaccinated until eradication occurs, must be our topmost research priority now.

The Nature of the Problem of Immunity and its Solution

“…Pasteur and his co-workers assumed that the mechanism by which complete immunity is obtained by means of vaccination with pathogens is that which eliminates such pathogens completely when upon illustrating the reality in which immune mechanisms bring about such immunity, I found complete immunity to have its origin in conditions that permit the influence of the pathogen on pathological mechanisms to be completely attenuated so that pathological manifestations are not brought about in response to the pathogen at all irrespective of high the load of such a pathogen may become. 7,8 5. Instead of evidence of the inability of pathogens to spread in an immune organism which Pasteur and co-workers expected on the basis of the logical deduction that the mechanisms that bring about immunity are those that defend the host by destroying pathogens which followed the logical deduction that the mechanism by which pathogens cause diseases is one in which the host is attacked, what they found was the consequence of the new theory of immunity that has emerged from the reality we have illustrated so farthat pathogens must necessarily develop very well in animals that enjoy complete immunity because the influence through which such pathogens cause diseases has been completely attenuated in them.…”

“…1 But the results obtained upon illustrating reality revealed that the evolutionary law is not the biological law by which species appeared on the planet. 8 In this reality, the evolutionary law is that according to which biological entities of different species become similar through convergent changes within a short period of time if they are exposed to the same conditions within such a period. 8 And the illustration of the reality in which the inflammatory responses that bring phagocytosing cells to sites of cell death in animals reveal the trigger of evolution to be mechanisms which do not exist for the good of the species but rather mechanisms which took control of the genetic information in their cells for a selfish purpose which may require them to destroy the organism if necessary.…”

“…8 In this reality, the evolutionary law is that according to which biological entities of different species become similar through convergent changes within a short period of time if they are exposed to the same conditions within such a period. 8 And the illustration of the reality in which the inflammatory responses that bring phagocytosing cells to sites of cell death in animals reveal the trigger of evolution to be mechanisms which do not exist for the good of the species but rather mechanisms which took control of the genetic information in their cells for a selfish purpose which may require them to destroy the organism if necessary. However, until the results that emerged from drawing further consequences from this reality revealed the evolutionary law to be the law according to which convergent changes occurred in the species and not the biological law according to which they appeared on the planet as Darwin inferred from analogy, I refrained from presenting this counterintuitive result of the reality in which inflammatory responses bring the phagocytosing cells of Mechnikov and other white blood cells into our tissues until such consequences were drawn.…”

“…Such changes include those which mineralized animal species in a manner that changed them, within a period that is so short, from forms which could not be preserved in rocks which they were at their origin to mineralized forms which can be preserved in such rocks so that their remains appeared suddenly in the lowest known fossiliferous rocks in the phenomenon known as the Cambrian explosion. 8 The changes of evolution must therefore be observed by our geneticists to be sudden outcomes of the struggle between such pathological mechanisms that control the genome to bring about changes which require the destruction of the organism under certain conditions and beneficial mechanisms which must necessarily repress such control when conditions permit them to make the necessary changes so that such pathological changes lose the beneficial appearance they have had in the absence of our illustration of reality when such conditions that permit repression disappear.…”

“…In the reality that yielded the observed consequence, the origin of the immunity we obtain by means of vaccination with an entity that is immunologically linked with the pathogen (such as the killed virus in the polio vaccine or the cowpox virus in the smallpox virus) is not the inflammatory response in which such antibodies are produced which we have viewed as an immune response in the absence of knowledge of the reality in which immune mechanisms protect us. 8 In this reality, the origin of such immunity lies in the conditions that permit immune mechanisms to obstruct the pathway through which such responses occur not only in response to the pathogen (such as the smallpox virus or polio virus) but also in response to etiological factors that are immunologically linked with it (such as the cowpox virus or the killed polio virus) which vaccination presents. 8 Asymptomatic infection rather than the prevention of infection by white blood cells and antibodies is the consequence of the complete immunity obtained by means of prior infection and vaccination when the protective conditions that permit complete attenuation are present.…”