The Other Medical Causes of Rhabdomyolysis

Allison, Ronald C.; Bedsole, D. Lawrence

doi:10.1097/00000441-200308000-00005

Cited by 131 publications

(100 citation statements)

References 42 publications

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“…Daha nadir görülen nedenler başlığı ise ilaçlar ya da toksinler, hipoksi, metabolik ve endokrin hastalıklar, enfeksiyonlar, ani ısı değişiklikleri ve diğer nedenler olarak ayrıntılan-dırılabilir. 3 Olgumuzun başvurusunda belirgin CPK enzim yüksekliği izlenmiştir. Bu duruma neden olabilecek travma, uzun süreli konvülsiyon, solunum ya da kardiyak arrest gibi bir öykü yoktu.…”

Section: Discussionunclassified

A Serious Rhabdomyolysis Associated with the Use of Quetiapine: Case Report

Keskin¹,

Ceylan²,

Karaca³

et al. 2015

Turkiye Klinikleri J Pediatr

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Section: Discussionunclassified

A Serious Rhabdomyolysis Associated with the Use of Quetiapine: Case Report

Keskin¹,

Ceylan²,

Karaca³

et al. 2015

Turkiye Klinikleri J Pediatr

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“…Some clinicians characterize it by the elevation of serum creatine kinase (CK) activity to at least ten times the upper limit of normal followed by a quick decline; while others consider a smaller increase in CK elevation (>5 times) sufficient for a diagnosis of rhabdomyolysis [1]. The diagnosis of rhabdomyolysis is dependent on the recognition of symptoms of muscle pain and weakness, the detection of current myoglobinuria or recent history, and elevated CK after ruling out other causes [2]. The severity of rhabdomyolysis ranges from asymptomatic elevation of CK to the life-threatening complications of acute renal failure and the development of severe electrolyte abnormalities.…”

Section: Introductionmentioning

confidence: 99%

“…A literature review of case reports, case series, and journal articles have shown the use of alcohol and other prescription medications have a higher incidence in causing rhabdomyolysis, and as many as 60% of patients have multiple concomitant etiologic factors attributing to a diagnosis of rhabdomyolysis [2] [4] [7] [8]. Trimethoprim-sulfamethoxazole (SMX-TMP) is an oral synthetic antibacterial combination product commonly used to treat urinary tract infections.…”

Section: Introductionmentioning

confidence: 99%

Sulfamethoxazole-Trimethoprim-Induced Rhabdomyolysis in an Immunocompetent Patient: A Case Report

Moye¹,

Manasen²,

O’Brien³

2017

CRCM

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Sulfamethoxazole-trimethoprim (TMP-SMX)-induced rhabdomyolysis is a rare complication of a commonly used antibiotic. This is a case report of a 43-year old immunocompetent African American woman with a history of depression and chronic alcohol consumption who presented to the emergency department (ED) with worsening bilateral leg pain. Before presentation, the patient was prescribed a twice daily dose of TMP-SMX for a urinary tract infection. The patient reported the development of intensifying leg pain after taking five doses of TMP-SMX. On presentation to the ED she was hemodynamically stable, afebrile, and leg pain intensity 10 out of 10. The patient admitted to daily alcohol consumption and taking vortioxetine 10 mg per day for treatment of depression. Initial labs drawn in the ED showed an elevated creatine kinase (CK) of 26,231 U/L and a normal serum creatinine (SCr) of 1 mg/dL. Through patient history and laboratory tests, common causes of rhabdomyolysis were ruled out. Treatment was initiated with IV fluids plus thiamine and folic acid supplementation, TMP-SMX was discontinued, and vortioxetine 10 mg per day was continued until hospital day five. The patient began to show improvement in lower extremity pain and tenderness and was discharged on hospital day eight with minimal residual leg pain and a CK of 2809 U/L. This case report presents only the third incidence of an immunocompetent patient developing TMP-SMX-induced rhabdomyolysis. This case highlights an opportunity for a pharmacist's intervention and the need for future research to determine risk factors of TMP-SMX-induced rhabdomyolysis in immunocompetent patients.

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“…Rhabdomyolysis, the release of muscle cell content into the plasma has a complex etiology [1,2]. Myoglobin, a low-molecular-mass protein found in striated muscles, is released within a few hours after injury [1].…”

Section: Introductionmentioning

confidence: 99%

Terlipressine Induced Rhabdomyolysis After Orthotopic Liver Transplantation

Eĭd

2014

J Med Cases

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In this report we present a fatal case of severe rhabdomyolysis during early recovery following a complicated but successful orthotopic liver transplantation. The key point in this case is skin necrosis and we consider that the clinical association of rhabdomyolysis and skin necrosis is a consequence of terlipressine induced severe vasoconstriction. A literature search was performed, in an attempt to identify similar cases as well as other plausible explanations.

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The Other Medical Causes of Rhabdomyolysis

Cited by 131 publications

References 42 publications

A Serious Rhabdomyolysis Associated with the Use of Quetiapine: Case Report

A Serious Rhabdomyolysis Associated with the Use of Quetiapine: Case Report

Sulfamethoxazole-Trimethoprim-Induced Rhabdomyolysis in an Immunocompetent Patient: A Case Report

Terlipressine Induced Rhabdomyolysis After Orthotopic Liver Transplantation

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