The outcome of adding peripheral neuromodulation (stoller afferent neuro-stimulation) to anti-muscarinic therapy in women with severe overactive bladder

Sancaktar, Murat; Ceyhan, Seyit Temel; Akyol, İlker; Muhçu, Murat; Alanbay, İbrahim; Ercan, Cihangir Mutlu; Atay, Vedat

doi:10.3109/09513591003649815

Cited by 25 publications

(24 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In comparison of PTNS and multimodal therapy, there was significant difference of symptoms episodes favouring multimodal therapy in a study by Sancaktar et al 40 and significantly higher response rate of multimodal therapy group compared to PTNS reported by Karademir et al 31 In the treatment of neurogenic OAB specifically, PTNS showed similar results. Kabay et al 41 evaluated 32 patients with Parkinson's disease accompanied with neurogenic detrusor DO.…”

Section: Efficacysupporting

confidence: 71%

Management of overactive bladder review: the role of percutaneous tibial nerve stimulation

Wibisono

Rahardjo

2017

Med J Indones

View full text Add to dashboard Cite

ABSTRAK ABSTRACTOveractive bladder (OAB) is a common condition that is experienced by around 455 million people (11% of the world population) and associated with significant impact in patients' quality of life. The first line treatments of OAB are conservative treatment and anti-muscarinic medication. For the refractory OAB patients, the treatment options available are surgical therapy, electrical stimulation, and botulinum toxin injection. Among them, percutaneous tibial nerve stimulation (PTNS) is a minimally invasive option that aims to stimulate sacral nerve plexus, a group of nerve that is responsible for regulation of bladder function. After its approval by food and drug administration (FDA) in 2007, PTNS revealed considerable promise in OAB management. In this review, several non-comparative and comparative studies comparing PTNS with sham procedure, anti-muscarinic therapy, and multimodal therapy combining PTNS and anti-muscarinic had supportive data to this consideration.

show abstract

Section: Efficacysupporting

confidence: 71%

Management of overactive bladder review: the role of percutaneous tibial nerve stimulation

Wibisono

Rahardjo

2017

Med J Indones

View full text Add to dashboard Cite

show abstract

“…In other RCTs, superiority of PTNS over placebo, and bladder training and PFMT was reported. Combination of PTNS plus antimuscarinics resulted in significantly better outcomes as compared with antimuscarinics alone . In a systematic review, four RCTs met their criteria for good quality .…”

Section: Types Of Neuromodulation (Table )mentioning

confidence: 99%

“…Percutaneous tibial nerve stimulation ( PTNS ) delivers neuromodulation to the pelvic floor through the S2‐4 junction of the sacral nerve plexus via the less invasive route of the posterior tibial nerve . Using the fine needle electrode insertion above the ankle, the tibial nerve is accessed.…”

Section: Types Of Neuromodulation (Table )mentioning

confidence: 99%

Neuromodulation for the Treatment of Lower Urinary Tract Symptoms

Yamanishi

Kaga

Fuse

et al. 2015

LUTS

View full text Add to dashboard Cite

Neuromodulation therapy incorporates electrical stimulation to target specific nerves that control lower urinary tract symptoms (LUTS). The objectives of this article are to review the mechanism of action, the type of neuromodulation, and the efficacy of neuromodulation mainly according to the results of randomized controlled trials. Neuromodulation includes pelvic floor electrical stimulation (ES) using vaginal, anal and surface electrodes, interferential therapy (IF), magnetic stimulation (MS), percutaneous tibial nerve stimulation, and sacral nerve stimulation (SNS). The former four stimulations are used for external periodic (short-term) stimulation, and SNS are used for internal, chronic (long-term) stimulation. All of these therapies have been reported to be effective for overactive bladder or urgency urinary incontinence. Pelvic floor ES, IF, and MS have also been reported to be effective for stress urinary incontinence. The mechanism of neuromodulation for overactive bladder has been reported to be the reflex inhibition of detrusor contraction by the activation of afferent fibers by three actions, i.e., the activation of hypogastric nerve, the direct inhibition of the pelvic nerve within the sacral cord and the supraspinal inhibition of the detrusor reflex. The mechanism of neuromodulation for stress incontinence is contraction of the pelvic floor muscles through an effect on the muscle fibers as well as through the stimulation of pudendal nerves. Overall, cure and improvement rates of these therapies for urinary incontinence are 30-50, and 60-90% respectively. MS has been considered to be a technique for stimulating nervous system noninvasively. SNS is indicated for patients with refractory overactive bladder and urinary retention.

show abstract

“…Six randomized trials provided data on the use of tibial nerve stimulation for treatment of urge urinary incontinence (39)(40)(41)(42)(43)(44). These trials included a total of 426 women, Peters et al had the largest sample analyzing 174 women (39).…”

Section: Tibial Nerve Electrical Stimulationmentioning

confidence: 99%

“…Three trials compared IVES and anticholinergic drugs (41)(42)(43). All reported significant improvement related to baseline in both groups, nevertheless, two of them found significant improvement PTNS group related to medication.…”

Section: Tibial Nerve Electrical Stimulationmentioning

confidence: 99%

Electrical Stimulation for Urinary Incontinence in Women: A Systematic Review

et al. 2013

View full text Add to dashboard Cite

Background: Electrical stimulation is commonly recommended to treat urinary incontinence in women. It includes several techniques that can be used to improve stress, urge, and mixed symptoms. However, the magnitude of the alleged benefits is not completely established. Objectives: To determine the effects of electrical stimulation in women with symptoms or urodynamic diagnoses of stress, urge, and mixed incontinence. Search Strategy: Our review included articles published between January 1980 and January 2012. We used the search terms "urinary incontinence", "electrical stimulation", "intravaginal", "tibial nerve" and "neuromodulation" for studies including female patients. Selection Criteria: We evaluated randomized trials that included electrical stimulation in at least one arm of the trial, to treat women with urinary incontinence. Data Collection and Analysis: Two reviewers independently assessed the data from the trials, for inclusion or exclusion, and methodological analysis. Main Results: A total of 30 randomized clinical trials were included. Most of the trials involved intravaginal electrical stimulation. Intravaginal electrical stimulation showed effectiveness in treating urge urinary incontinence, but reported contradictory data regarding stress and mixed incontinence. Tibial-nerve stimulation showed promising results in randomized trials with a short follow-up period. Sacral-nerve stimulation yielded interesting results in refractory patients. Conclusions: Tibial-nerve and intravaginal stimulation have shown effectiveness in treating urge urinary incontinence. Sacral-nerve stimulation provided benefits in refractory cases. Presently available data provide no support for the use of intravaginal electrical stimulation to treat stress urinary incontinence in women. Further randomized trials are necessary to determine the magnitude of benefits, with long-term follow-up, and the effectiveness of other electrical-stimulation therapies.

show abstract

The outcome of adding peripheral neuromodulation (stoller afferent neuro-stimulation) to anti-muscarinic therapy in women with severe overactive bladder

Abstract: Combining SANS and anti-muscarinic therapy resulted in significantly better clinical outcomes and IIQ-7 scores as compared with anti-muscarinic treatment alone in patients with severe overactive bladder.

Cited by 25 publications

References 15 publications

Management of overactive bladder review: the role of percutaneous tibial nerve stimulation

Management of overactive bladder review: the role of percutaneous tibial nerve stimulation

Neuromodulation for the Treatment of Lower Urinary Tract Symptoms

Electrical Stimulation for Urinary Incontinence in Women: A Systematic Review

Contact Info

Product

Resources

About