The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort

Abstract

Most children with JIA managed with contemporary treatments attain inactive disease within 2 years of diagnosis and many are able to discontinue treatment. The probability of attaining remission within 5 years of diagnosis is about 50%, except for children with polyarthritis.

Management of Juvenile Idiopathic Arthritis 2015: A Position Statement from the Pediatric Committee of the Canadian Rheumatology Association

“…The result is that clinical outcome has improved and complete disease control can often be achieved 1 .…”

Treatment in juvenile rheumatoid arthritis and new treatment options

“…These drugs decrease pain by analgesic effect at low doses, but have antiinflammatory effect at higher doses. In the first 1-3 days of treatment, a response in the form of decreased pain is obtained (1)(2)(3)11).…”

“…In addition, the patient's preference should be considered in terms of the mode of administration and frequency of administration. The limitations for use of these drugs include inadequate long-term safety data and cost, though they are efficient drugs (1)(2)(3)(11)(12)(13)(14).…”

“…It is not recommended to be used in systemic JIA, since the risk of side effects is increased. The initial dose is 10-20 mg/kg/day and the dose is increased to 30-50 mg/kg/day in weeks (1)(2)(3)(11)(12)(13)(14).…”

Participation in Leisure Activities among Canadian Children with Arthritis. A Wakeup Call for Physicians

“…Canadian researchers have demonstrated that patients with JIA (except rheumatoid factor-positive polyarticular JIA) have a 70-90% chance of attaining inactive disease by 2 years postdiagnosis 2 . Inactive disease was defined using modified Wallace criteria 3 .…”