The Bangkok Metropolitan Area is an example of urban sprawl that has undergone rapid expansion and major changes in urban composition and building configuration. This city is now faced with the urban heat island phenomenon. Initial observations of land surface temperature (LST) in recent years have indicated that LST has tended to increase in both urban and suburban areas. The purposes of this study were to: (1) assess different land cover types and combinations of land cover composition along an LST gradient, and (2) investigate effect of building configuration types on the LST in densely urban areas. We analyzed the urban composition variation of 4,960 land cover samples using a 500 m × 500 m grid and configuration metrics in spatial patterns from Landsat 8 data and a high-resolution database of buildings obtained from GIS data of the Bangkok Metropolitan Area. The results indicated that the fraction of land cover composition was strongly related to LST. Our results suggested that LST can be effectively mitigated by using below green (shrubs, grasses, and yards), above green (trees, orchards, mangroves, and perennial plants) and water land cover. By increasing tree canopy to around 20%, water body to around 30% or green yard/shrub to around 40% of the built-up areas, it is possible to reduce LST significantly. Urban configurations (edge density, patch density, large patch, mean patch size, building height, compactness of building, building type, and building use) affecting on LST were studied. Increased edge density, patch density of buildings, and building height caused reductions in LST. Distribution of LST patterns can be significantly related with urban composition or land configuration features. The results of this study can increase understanding of the interaction between urban composition and configuration metrics. Moreover, our findings may be useful in the mitigation of the impact of LST in urban-sprawl cities.