The Pathology of Vitreous Hemorrhage

Ocular manifestations of Pregnancy Induced Hypertension

“…[5][6][7]12,26 Spontaneous vitreous haemorrhage and bilateral retinal neovascularization regressing after delivery have been reported in PIH with clotting abnormalities. [27][28][29][30] Retinal Detachment should be differentiated from circumscribed neurosensoryretinal detachment of the posterior pole -Central Serous Chorioretinopathy (CSR) associated with pregnancy. …”

Fibrinogen-induced Vitreous Membranes

“…Fibrin has been demonstrated in the vi treous cavity in vitreous hemorrhage by bio chemical [13], histopathologic [14,15,38], and electron microscopic techniques [15]. Intravitreal fibrinolysis has an important role in the clearing of vitreous hemorrhage [13,39] and has been detected in the vi treous of healthy human, monkey, dog, sheep, and calf eyes [16,40].…”

“…Fibrin was incriminated in the causation of corneal neovascularization [6,7], chronic uveitis [8], congenital glaucoma [9,10], chronic open-angle glaucoma [11], and Fuchs' dystrophy [12], Fibrin has been dem onstrated biochemically [13] and histopathologically [14,15] in vitreous hemor rhage. Fibrinolysis along with hemolysis and phagocytosis constitute the three main pro cesses involved in the resolution of vitreous hemorrhage [13][14][15][16][17][18]. Intravitreal fibrin was demonstrated by electron microscopy in an eye with the postvitrectomy syndrome [19].…”

Clinical assessment of retinopathy post management of pregnancy induced hypertension

“…[12] Cases of optic atrophy following detachment have been reported. Spontaneous vitreous hemorrhage [20] and bilateral retinal neovascularization [21,22] regressing after delivery has been reported in PIH with clotting abnormalities. [23] …”