The Pharmacological Potential of Mushrooms

Lindequist, Ulrike; Niedermeyer, Timo H. J.; Jülich, Wolf-Dieter

doi:10.1093/ecam/neh107

Cited by 833 publications

(642 citation statements)

References 107 publications

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“…Bioactive potential of wild mushrooms are increasingly recognised owing to a wide range of properties like radical-scavenging, antimicrobial, anticancer, antidiabetes, hepatoprotective, cosmeceutical and nutricosmetic potentials (Lindequist et al 2005; Biswas et al 2011b; Kalogeropoulos et al 2013; Shameem et al 2015; Smith et al 2015; Taofiq et al 2016). Recently, mushroom-based antioxidants have attracted wide attention worldwide against synthetic antioxidants (e.g.…”

Section: Resultsmentioning

confidence: 99%

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

et al. 2016

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The wild mushroom Astraeus hygrometricus is a traditional delicacy during the monsoon season in South-western India. Bioactive principles and antioxidant potential of uncooked and pressure-cooked tender mushroom have been evaluated. Seven bioactive principles of mushroom (tannins, flavonoids, vitamin C, phytic acid, lycopene, β-carotene and trypsin inhibition) were significantly higher, while total phenolics content was significantly lower in uncooked than in cooked samples. Mushroom was devoid of L-DOPA, whereas only uncooked samples showed haemagglutinin activity against A+ blood group. The principal component analysis of uncooked mushroom showed only two bioactive principles clustered with two antioxidant properties, while in cooked mushroom five bioactive principles clustered with three antioxidant properties depicting the nutraceutical potential of cooked mushroom. Future studies should focus on appropriate thermal treatment, which retain maximum bioactive and antioxidant potential to combat health- and lifestyle-related ailments. The A. hygrometricus is ectomycorrhizal, conservation of its host tree species is utmost importance in improvement and expansion of its yield to sustain food security and economic gains of local tribals.

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Section: Resultsmentioning

confidence: 99%

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

et al. 2016

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“…Polysaccharides are one of the biologically active groups of compounds found in mushrooms, namely in Ganoderma genus, which have antitumor properties (Wasser, 2002;Lindequist et al, 2005;Paterson, 2006;Ferreira et al, 2010;Patel and Goyal, 2012;Nie et al, 2013). Thus, Ganoderma has been considered a bioactive therapeutic fungus (Paterson, 2006) and its antitumor potential has been explored (Wang et al, 1997;Yuen and Gohel, 2005).…”

Section: Structure-bioactivity Relationshipmentioning

confidence: 99%

Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities

et al. 2015

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This review aims to contribute to the growing knowledge on bioactive (antioxidant, antitumor and antimicrobial) properties of polysaccharides, glycoproteins and polysaccharidic extracts obtained from Ganoderma species. The chemical features were analyzed and related to correspondent bioactivities. ____________________________________________________________________ 2 Research highlightsChemical features of Ganoderma bioactive polysaccharides were discussed.Methods for extraction, isolation and identification were evaluated.Bioactivity of polysaccharidic extracts and purified compounds were discussed.Integration of data allowed deduction of structure-activity relationships.

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“…Presently they are significantly consumed in western countries (Lindequist, Niedermeyer, & Julich, 2005). The main commercial mushrooms are Agaricus bisporus L., Lentinus edodes (Berk.)…”

Section: Introductionmentioning

confidence: 99%

Anti-inflammatory potential of mushroom extracts and isolated metabolites

Taofiq

Martins

Barreiro

et al. 2016

Trends in Food Science & Technology

108

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Background: In the recent years natural resources are being in focus due to their great potential to be exploited in the discovery/development of novel bioactive compounds and, among them, mushrooms can be highlighted as alternative sources of anti-inflammatory agents. Scope and approach:The present review reports the anti-inflammatory activity of mushroom extracts and of their bioactive metabolites involved in this bioactive action.Additionally the most common assays used to evaluate mushrooms anti-inflammatory activity were also reviewed, including in vitro studies in cell lines, as well as in animal models in vivo. Key findings and conclusions:The anti-inflammatory compounds identified in mushrooms include polysaccharides, terpenes, phenolic acids, steroids, fatty acids and other metabolites.Among them, polysaccharides, terpenoids and phenolic compounds seem to be the most important contributors to the anti-inflammatory activity of mushrooms as demonstrated by numerous studies. However, clinical trials need to be conducted in order to confirm the effectiveness of some of these mushroom compounds namely, inhibitors of NF-κB pathway and of cyclooxygenase related with the expression of many inflammatory mediators.

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The Pharmacological Potential of Mushrooms

Cited by 833 publications

References 107 publications

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities

Anti-inflammatory potential of mushroom extracts and isolated metabolites

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