The pharmacological treatment of acute colonic pseudo‐obstruction

Giorgio, Roberto De; Barbara, Giovanni; Stanghellini, Vincenzo; Tonini, Marcello; Vasina, Valentina; Cola, Bruno; Corinaldesi, Roberto; Biagi, Giacomo; Ponti, Fabrizio De

doi:10.1046/j.1365-2036.2001.01088.x

Cited by 111 publications

(116 citation statements)

References 86 publications

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“…Appropriate caloric support must be provided by IV infusion. Erythromycin, somatostatin and neostigmine can be used to promote transit and decrease the duration of acute episodes [61][62][63] .…”

Section: Treatment Of the Acute Phasementioning

confidence: 99%

Chronic intestinal pseudo-obstruction

Antonucci¹,

Fronzoni²,

Cogliandro³

et al. 2008

WJG

190

238

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Section: Treatment Of the Acute Phasementioning

confidence: 99%

Chronic intestinal pseudo-obstruction

Antonucci¹,

Fronzoni²,

Cogliandro³

et al. 2008

WJG

190

238

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“…The pathogenesis of Ogilvie's syndrome or ACPO has been explained by Abnormalities of the autonomic nervous system, particularly dysfunction of parasympathetic system and the underlying pathophysiology, whatever the cause, is an early motor disturbance followed by complete impairment of gut peristalsis with progressive dilatation (De Giorgio et al, 2001). However, the pathogenesis of ACPO in patients with SCD is unclear, this is because not only previous studies have shown no evidence of gut ischemia, micro vascular or macro vascular occlusion in these patients but also the disorders associated with acute colonic pseudo obstruction have been ruled out in studied patients and all investigations failed to clarify a cause for this manifestation (Knox-Macaulay et al, 2003).…”

Section: Discussion:-mentioning

confidence: 99%

“…It is a poorly understood syndrome, characterized by symptoms, signs and radiological pattern of the large bowel obstruction with no evidence of mechanical obstruction (De Giorgio et al, 2001;Singh et al, 2005). Typically ACPO occurs in patients with serious illnesses, surgical interventions, infections, burns, trauma and narcotic administration (Gmora et al, 2002).…”

Section: Introduction:-mentioning

confidence: 99%

Sickle Cell Disease-Induced Ogilvie’s Syndrome in a Child Treated Pharmacologically With Neostigmine: A Case Report.

Fouda¹,

Anwar²,

JS³

et al. 2016

IJAR

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“…Medical managements include drugs like metoclopramide and neostigmine. Neostigmine (a reversible acetylcholinersterase inhibitor that stimulates the colon) is the best evaluated medical treatment with published success rates of up to 50 per cent of patients [14,15].…”

Section: Discussionmentioning

confidence: 99%

Recurrence of Ogilvie’s Syndrome, a Rare Postoperative Complication in Second Caesarean Section

2016

J Syndr

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Acute colonic pseudo obstruction (ACPO), also known as Ogilvie's syndrome is a very rare postoperative complication of Caesarean section. It has classically been reported in critically ill patients and following cardiac and hip surgery. Whether this complication recurs in subsequent operations is not known. Only one case report of recurrence following caesarean section was found in literature survey. We report a case of Ogilvie's syndrome which recurred in the second Caesarean section and was successfully managed conservatively. IntroductionOgilvie's syndrome or acute colonic pseudo obstruction (ACPO) is a rare but potentially fatal postoperative complication which is characterised by severe adynamic ileus with massive colonic dilatation in the absence of mechanical obstruction. Sir William Heneage Ogilvie described this syndrome in 1948 which was subsequently named after him. It has an incidence of 0.1% approximately following major surgeries [1] like cardiac and hip surgery [2,3]. In women, caesarean section appears to be the most common surgery associated with Ogilvie's syndrome [4].We report a case of recurrent Ogilvie's syndrome in two consecutive Caesarean sections in a patient with severe pre-eclampsia. On both occasions she was successfully managed conservatively. This case is unique because it seems to be the second such reported case of post cesarean section recurrent Ogilvie's syndrome (MEDLINE with search terms pseudo obstruction, post caesarean, and recurrence). Given the rising trend of caesarean sections, it is intuitive that this rare syndrome may not remain rare in the future. Obstetricians thus need to have awareness regarding the features, preventive measures and early recognition and management of this complication because patients may have to undergo cesarean sections in more than one occasions in her lifetime. Case PresentationA 33 years old P2+0 with 2 previous caesarean sections was referred to our hospital with gradual distension of abdomen from the 5 th postoperative day of Caesarean section. She had no stool since operation but was passing flatus without any vomiting or fever. She had undergone emergency Caesarean section under spinal anaesthesia in a peripheral health unit for severe pre-eclampsia in a post caesarean pregnancy.The operative notes in the referral card mentioned that she Case Report Open Access Journal of Syndromeshad an episode of postpartum haemorrhage on the operation table which was managed by syntocinon drip, prostaglandin F2 ɑ (250 mcg I.M) and per rectal misoprostol (800 mcg). The estimated blood loss was around 1000 ml which was replaced with crystalloids and

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The pharmacological treatment of acute colonic pseudo‐obstruction

Cited by 111 publications

References 86 publications

Chronic intestinal pseudo-obstruction

Chronic intestinal pseudo-obstruction

Sickle Cell Disease-Induced Ogilvie’s Syndrome in a Child Treated Pharmacologically With Neostigmine: A Case Report.

Recurrence of Ogilvie’s Syndrome, a Rare Postoperative Complication in Second Caesarean Section

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