The physiology and pharmacology of singlet oxygen

Stief, T.

doi:10.1016/s0306-9877(03)00026-4

Cited by 127 publications

(86 citation statements)

References 107 publications

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“…Superoxide anions are reactive species produced by transfer of one electron and involves in the formation of other reactive oxygen species such as hydrogen peroxide, hydroxyl radical or singlet oxygen in living system (Stief, 2003). Because of scavenging power, antioxidants turn to be effective in managing with disease like ulcer, stomach problems, cancer and AIDS.…”

Section: Discussionmentioning

confidence: 99%

Tuber Extract Mediated Biosynthesis of Silver Nanoparticles and its Antioxidant, Antibacterial Activity

Sivakumar¹,

Gajalakshmi²,

Subramania³

et al. 2015

J. of Biological Sciences

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A B S T R A C TThe biosynthesis of silver nanoparticles by the reduction of aqueous silver metal ions during revelation to both fresh, dry tuber extract and in vitro antioxidant, antibacterial activity of sweet potato were studied. Tuber extract of sweet potato was prepared for the synthesis of silver nanoparticles under different reaction time. The prepared materials were characterized by UV-visible spectroscopy, X-Ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FT-IR). During incubation period, the intensity of colour increased and its characteristic absorption was recorded at 428 and 439 nm. X-ray diffraction showed that the average particles size 4.77 and 5.6 nm. The FT-IR spectra of the tuber extract and synthesized silver nanoparticles revealed the reducing and capping actions of biomolecules such as amine, peptide, amide, lactone, polyphenol groups in protein linkages and it was found to be involved in the stabilization and biosynthesis of AgNPs. Scanning Electron Microscopy (SEM) showed silver nanoparticles was pure and the sizes were ranging from 1-10 µm. Green synthesized silver nanoparticles exhibited strong antioxidant and effective antibacterial activity against human pathogenic bacteria. Thus, green synthesis seems to be cost effective and alternate to conventional methods of silver nanoparticles synthesis. No synthetic reagent were used in this investigation and thus it is an environmentally safe method with potential for biomedical and agriculture application.

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Section: Discussionmentioning

confidence: 99%

Tuber Extract Mediated Biosynthesis of Silver Nanoparticles and its Antioxidant, Antibacterial Activity

Sivakumar¹,

Gajalakshmi²,

Subramania³

et al. 2015

J. of Biological Sciences

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“…These benefits are the activation of nuclear transcription factors, gene expression and destructive effect to tumor cells and microorganisms (Packer & Weber, 2001). Superoxide radicals (O•-2) act as controller for the growth of cells (Bhattacharyya et al, 2014); in addition, it can assault a lot of pathogens stimulating inflammatory responses (Stief, 2003). Nitric oxide (NO•) is signaling molecules participating in cellular and organ function as a neurotransmitter and a mediator of the immune responses (Fang et al, 2002).…”

Section: Free Radicals and Oxygen And Lipid Peroxidationmentioning

confidence: 99%

Antioxidant activity of vitamin e and its role in avian reproduction

Tufarelli

Laudadio²

2016

JEBAS

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Oxidative stress, a state characterized by imbalance between pro-oxidant molecules comprising reactive oxygen and nitrogen species, and antioxidant defences, has been found to play an important in poultry reproduction in both male and female Increasing evidence suggests that vitamin E plays an important role in normal reproduction in animals and humans, and vitamin E supplementation is now recommended. Vitamin E comprises eight molecules composed by a chromanol ring and a phytol side chain having same functions: four tocopherols (α, β, γ, and δ) and four tocotrienols (α, β, γ, and δ). This article reports an overview on the currently available literature on the role of reactive species and oxidative stress in avian reproductive processes. Current evidences demonstrate that dietary vitamin E supplementation may be effective in controlling the production of reactive oxygen species and continue to be explored as a potential feeding strategy to support avian reproduction.

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“…In fact, 1 O2 may be harmful due to its ability to react with DNA, lipids and proteins inhibiting their normal function, and such changes are involved in the development of cancer, cardiovascular diseases and aging process. [1][2][3] For this reason, the development of in vitro screening methodologies to assess the scavenging effects of biologically active compounds and therapeutic drugs against 1 O2 is extremely important. In this context, several methods for evaluation of reactivity towards 1 O2, have been reported, based on electron spin resonance (ESR) 4,5 and absorbance, 6,7 fluorescence, 8,9 direct near-infrared luminescence 10,11 and chemiluminescence (CL) 12,13 measurements.…”

Section: Introductionmentioning

confidence: 99%

“…The proposed system used solenoid micro-pumps as the only active components of the flow manifold, enabling the reproducible insertion and efficient mixing of sample and reagents as well as the transportation of the sample zone towards detection for chemiluminescence measurement, assuring a strictly reproducible timing of all analytical tasks. Several compounds were evaluated as possible 1 Furthermore, MPFS are computer-controlled systems offering a reproducible mixing of solutions, excellent precision on timing events and more flexibility concerning the method development and operation since any changes in the parameters are accomplished using software control. 18 One of the main purposes of this work is to study the reactivity of several compounds towards 1 O2 and evaluate their possible scavenging capacity.…”

Section: Introductionmentioning

confidence: 99%