The phytochemistry and medicinal value of Psidium guajava (guava)

Naseer, Sumra; Hussain, Shabbir; Naeem, Naureen; Pervaiz, Muhammad; Rahman, Madiha

doi:10.1186/s40816-018-0093-8

Cited by 230 publications

(155 citation statements)

References 53 publications

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“…It is interesting to note, that the extended fermentation period will encourage the phenolic material and the antioxidant operate but will not raise the acidic flavour. Owing to greater antioxidant action and elevated prospective safety advantages, 12 days of fermentation are proposed not more as the reduction of both the phenolic content and that of the antioxidant action and the microbial population for kombucha tea used with the substrate have been noted (Muhialdin et al, 2019). acetic acid and catechins have been well informed about the potential to inhibit a range of gram-positive and gram-negative microorganisms (Jayabalan et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

Khaleil¹

2020

JMBFS

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Acetobacter aceti, Acetobacter pasteurianus, Gluconobacter oxydans, and yeasts mostly Saccharomyces sp., Zygosaccharomyces kombuchaensis, Torulopsis sp., Pichia membranaefaciens, Brettanomyces sp. (Borkani et al., 2016). The main component of Kombucha tea is the light cellulose pellicle layer and the sour liquid broth (Goh et al., 2012). The microbes accumulate forming a firm cellulosic biofilm in the liquid-air interface during fermentation. which may act as a public good providing protection from invaders, storage for resources, and greater access to oxygen for microbes embedded within it (May et al., 2019). On the other hand, the majority of the biofilms examined so far are shaped either on a liquid-solid or air-solid interface (Chakravorty et al., 2016a). Kombucha tea can be generated when the cultivation medium is supported by the high values of nitrogen sources in the form of purine derivatives like caffeine and theophylline for tea fungus culture (Malbasa, 2004). In general, the substratum of fermenting kombucha, i.e. green or black tea extract is sugared by addition of 5 to 8 % sucrose and in addition to these traditionally substrates alternative substrates have been addressed such as Pepsi, grape juice, balsamic vinegar, vinegar, Jerusalem artichoke extract and milk (Essawet et al., 2015). Later, the several trails are being approved by the preparation of kombucha by substrates, other than black and green teas, such as Jerusalem artichoke tuber extracts, wine, milk, fruit juices and medicinal herbs like lemon balm, thyme, peppermint and sage (Jayabalan et al., 2014; Velićanski et al., 2013). At the end of the fermentation process, the chemical composition analysis in Kombucha foucsed on the active constiuents which confer to the fermented beverage its nutritional and antioxidant value, Kombucha is rich in organic acids (acetic, glucuronic, gluconic acids), vitamins and tea polyphenols (Jayabalan et al., 2014). Recently, (Jayabalan et al., 2007) characterized the fermentation process of guava leaves infusions by kombucha and studying possible chemical changes in their polyphenolic profile. The antimicrobial activity of Kombucha against pathogenic microorganisms is primarily attributed to antibiotics, acetic acid and other metabolites that generated in it (Sreeramulu et al., 2000a, 2001a). These metabolites are mainly polyphenols and tannins, which significantly inhibit a broad spectrum of gram-positive and negative bacteria. Later, the anti-Kombucha has become a flavored tea drink fermented with a symbiotic community of fungi, yeast, and bacteria. Kombucha has been reported to show functional medicinal importance attributed to the presence of some critical metabolites and bioactive compounds. We developed kombucha on three different substrates like black tea, green tea, and Psidium guajava (guava) juice extract. Kombucha enriched with guava extract showed maximal growth in terms of weight (fresh and dry) and moisture percentage. Further, the total phenol, total flavonoid, and characterization of different...

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Section: Discussionmentioning

confidence: 99%

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

Khaleil¹

2020

JMBFS

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“…Psidium guajava (guava) is known for its fruit and medicinal purposes in the tropical countries. Guava is indicated for the treatment of gastroenteritis, caries, diarrhea, dysentery, diabetes, hypertension and pain relief (Naseer et al, 2018). It contains high content of organic and inorganic compounds such as antimicrobials, antioxidants, polyphenols and anti-inflammatory compounds (Naseer et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

In vitro antibacterial activity of Psidium guajava (Guava) leaves extract on carbapenem-resistant Klebsiella pneumoniae causing multi-drug resistant systemic infections

Hackman¹,

Arhin²,

Azumah³

et al. 2020

J. Med. Plants Res.

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Systemic bacterial infections affect almost all part of the human body systems leading to infections such as urinary tract infections, septicemia, meningitis, pneumonia, peritonitis and gastritis. Carbapenems have been used as drug of choice in the treatment of systemic infections. Studies have indicated that Enterobacteriaceae are producing enzymes such as carbapenemases, which inactivate carbapenems. There is limited treatment option for systemic infections caused by carbapenemresistant Enterobacteriaceae. Systemic infections keep increasing; hence, the determination of the effective treatment options of carbapenem-resistant Enterobacteriaceae is important for quality healthcare delivery. In this laboratory studies, agar well diffusion and well microplate dilution of the ethanolic extract of the guava leaves was used to determine the effectiveness of Psidium guajava on carbapenem-resistant K. pneumoniae. The antimicrobial compounds responsible for the antibacterial activity were screened using standard methods. The active zones of inhibition were observed in P. guajava leaves extract concentrations of 50, 100 and 200 mg/ml. The minimum inhibition concentration and minimum bactericidal concentration of ethanolic extract of guava leaves was 6.25 mg/ml indicating significant antibacterial activity against the carbapenem-resistant K. pneumoniae. The antibacterial activity of the leaves extract may be attributed to the presence of flavonoids and other antimicrobial phytochemicals in the guava leaves extract. The outcome of this baseline laboratory studies indicates the possibility of producing efficacious antibiotic to treat carbapenems-resistant systemic infections. The determination of the toxicological effect of the isolated active antimicrobial compounds of guava leaves extract is worth following in subsequent studies.

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“…is a medicinal plant belonging the family Myrtaceae and found in the many places of India. The leaves and fruits are used for the traditional medicine worldwide [1][2][3][4] . In India, the fruits are edible food crop as low cost compared to other fruits and poor people can also afford as food 3,5 .…”

Section: Introductionmentioning

confidence: 99%

“…tannins, phenols, triterpenes, βavonoids, essential oils, saponins, carotenoids, lectins, vitamins, fibre and fatty acids [5][6][7][8][9][10] that prevent several diseases such as digestive disorders, cancers and mutations, bacterial infection, menstrual disorders, dermatitis, neurodegenerative disease, diabetes, lung problems, free radical generation, etc. [4][5][6][11][12][13] .…”

Section: Introductionmentioning

confidence: 99%

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Presence of phytochemicals in fruits and leaves of guava (Psidium guajava Linn.) for cancer prevention: A mini review

Biswas

Talukdar²,

Talapatra

2019

J. Drug Delivery Ther.

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The present review deals with the bioactive compounds (phytochemicals) in the fruits and leaves of guava (Psidium guajava Linn.). In the present study, an attempt was done to survey of literatures for exact solvent extraction to know exact phytocompound and characterization by using instruments along with anticancer properties of these phytochemicals present in fruits and leaves of guava. The compilation of available literatures of last 10 years can be suitable ready references for future experimental study as in vitro and in vivo as well as new drug design as phytomedicines for cancer therapy. Keywords: Bioactive compounds, Psidium guajava, Guava fruits and leaves, Cancer therapy, Phytomedicines

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The phytochemistry and medicinal value of Psidium guajava (guava)

Cited by 230 publications

References 53 publications

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

In vitro antibacterial activity of Psidium guajava (Guava) leaves extract on carbapenem-resistant Klebsiella pneumoniae causing multi-drug resistant systemic infections

Presence of phytochemicals in fruits and leaves of guava (Psidium guajava Linn.) for cancer prevention: A mini review

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