Psidium guajava (guava) is well known tropic tree which is abundantly grown for fruit. Many countries have a long history of using guava for medicinal purposes. This plant finds applications for the treatment of diarrhea, dysentery, gastroenteritis, hypertension, diabetes, caries and pain relief and for improvement in locomotors coordination. Its leaf's extract is being used as a medicine in cough, diarrhea, and oral ulcers and in some swollen gums wound. Its fruit is rich in vitamins A, C, iron, phosphorus and calcium and minerals. It contains high content of organic and inorganic compounds like secondary metabolites e.g. antioxidants, polyphenols, antiviral compounds, anti-inflammatory compounds. The phenolic compounds in guava help to cure cancerous cells and prevent skin aging before time. The presence of terpenes, caryophyllene oxide and p-selinene produces relaxation effects. Guava leaves contain many compounds which act as fungistatic and bacteriostatic agents. Guava has a high content of important antioxidants and has radio-protective ability. Quercetin is considered as most active antioxidant in the guava leaves and is responsible for its spasmolytic activity. Its ethyl acetate extract can stop the germ infection and thymus production. Guava possesses anti-viral, anti-inflammatory, anti-plaque and anti-mutagenic activities. Guava extract shows antinociceptive activity and is also effective in liver damage inflammation and serum production. Ethanolic extract of guava can increase the sperm quality as well as quantity and can be used for the treatment of infertile males.

This paper investigates the existing journalistic practices in three deadly conflicts in Pakistan and also proposes corrective peace-oriented media strategies. Based on semi-structured interviews with journalists, analysts and stakeholders involved in the religiously inspired Taliban conflict, separatist-led Balochistan conflict and the ethno-political conflict in Karachi, six strategies have been identified. These include highlighting the problems of sufferers and contextualization of the Taliban conflict; inclusion of multi-perspectives and highlighting the voices of peacemakers in the Balochistan conflict; humanization and solution-oriented coverage of the ethno-political conflict in Karachi. While the journalists agreed these strategies were very much in line with their professional duties, the analysts and stakeholders hoped the proposed journalistic practices would lead to better understanding and facilitate resolution of the three conflicts. Based on the findings of this article, the researchers advocate a pragmatic form of peace journalism that reflects the ground realities as compared to the more critical form of peace journalism that becomes difficult to be practiced in conflict scenarios.

New organotin(IV) carboxylates, R 2 SnL 2 (R = n-Bu: 1), R 2 Sn(Cl)L (R = n-Bu: 2) and R 3 SnL (R = Me: 3; n-Bu: 4; Ph: 5), have been synthesized by stirring 5-chloro-2-hydroxybenzoic acid HL with KOH and R 2 SnCl 2 (R = n-Bu)/R 3 SnCl (R = Me, n-Bu, Ph) in methanol at room temperature. The complexes along with ligand have been characterized by FT-IR, ( 1 H, 13 C) NMR, EI-MS and single crystal XRD crystallography. FT-IR data indicated bidentate coordination of carboxylate. NMR data suggested six-or five-coordinate geometry of organotin(IV) carboxylates. Single crystal XRD of 1 demonstrated skew-trapezoidal geometry around the tin center, with the basal plane occupied by four oxygens and the two butyl groups lying in distorted axial position. Complexes 1, 2 and 5 exhibited interaction with SS-DNA (salmon sperm) and suggests intercalating mode of binding. The complexes displayed significant antimicrobial activities against bacterial and fungal strains as compared to free ligand. The hemolytic activity of the complexes was lower compared to Triton-X 100 (positive control, 100% lysis) and higher than PBS (negative control, 0% lysis). Complex 4 was the most potent inhibitor of bacterial/fungal growth.

The objective of the study was to explore the incidence of patulin (PAT) mycotoxin in mango and orange fruits and derived products marketed in Pakistan. A total of 274 samples, including 70 mango fruits, 63 mango-based products (juices, pulp, and jam), 77 orange fruits, and 64 orange-based products, were collected. PAT was determined by reverse-phase high-performance liquid chromatography (HPLC) with UV-Vis detector (276 nm). Linear detector response was observed (R2 > 0.99), the limit of detection (LOD) was 5 µg/kg and recovery percentage was 97.4%. The incidence of PAT in mango samples was 61.7%, and the concentration ranged from <LOD to 6415 µg/kg with a mean of 110.9 µg/kg. Our results showed the high susceptibility of mango fruits to patulin, and it was observed that decayed mango fruits were most contaminated with PAT. Among the mango samples, PAT concentration was higher in fruits than in processed products such as mango juice, pulp, and jam. Toxin incidence in orange samples was 52.5% with concentrations from <LOD to 61 µg/kg and a mean of 6.3 µg/kg. As much as 29 samples of mango (21.8%) contained PAT concentration above the regulatory limit (50 µg/kg), whereas there was only one exceeding orange sample (0.7%). Our results show that PAT seems to be a problem in fruits, juices, and derived solid products, especially from mango, and needs surveillance on regular basis.