1994
DOI: 10.1002/rmv.1980040405
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The place of DTP/eIPV vaccine in routine pediatric vaccination

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Cited by 18 publications
(4 citation statements)
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“…At 37ºC there is a significant loss of potency of the type 1 component after 1-2 days and of types 2 and 3 after 2 weeks (120,143). Freezing diminishes potency of IPV, related to loss of the D-antigen structure (143).…”
Section: Inactivated Poliomyelitis Vaccinementioning
confidence: 99%
“…At 37ºC there is a significant loss of potency of the type 1 component after 1-2 days and of types 2 and 3 after 2 weeks (120,143). Freezing diminishes potency of IPV, related to loss of the D-antigen structure (143).…”
Section: Inactivated Poliomyelitis Vaccinementioning
confidence: 99%
“…IgA induced in the gut plays an important role in terminating primary infection in the intestinal tract and the tonsils [4,203] affecting both fecal-oral and oral-oral transmission. In practice, IPV also induce some intestinal immunity although less than OPV, and the duration of excretion in individuals immunized with IPV appears to be longer [24,94,[207][208][209].…”
Section: Poliovirus Infections At the Level Of The Individual Hostmentioning
confidence: 99%
“…The original IPV formulation has since been improved. This enhanced IPV, eIPV, has a higher immunogenicity and protective efficacy than IPV [208]. A number of factors contributed to this improvement.…”
Section: Poliovirus Infections At the Level Of The Individual Hostmentioning
confidence: 99%
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