The plasma cells of the cerebrospinal fluid

“…In our case 1 of zoster meningitis, the CSF specimen taken 5 days after the onset of the skin rash showed many blast forms -large lymphocytes and immature plasma cells, which is considered to be a sign of acute viral menin gitis (21,22). Tire CSF cells of the same case and of 3 other cases, taken 15 and 11-14 days, respectively, after the onset of the skin rash consisted of small lymphocytes, mature plasma cells and monohistiocytes, which is indicative of the convalescent phase.…”

Section: Discussionmentioning

confidence: 99%

“…In the acute phase, blast forms -large or 'trans formed' lymphocytes and some plasma cells including 'immature' types -are observed in addition to the neutrophilic reaction. In the convalescent phase, these cells are replaced by small lymphocytes, 'mature' plasma cells and monohistiocytes (17,(21)(22)(23). Dommasch etal.…”

Section: Discussionmentioning

confidence: 99%

“…As to the lymphocytes and plasma cells, large lymphocytes and immature plasma cells were differentiated and counted separately. Plasma cells with large nuclei and deeply stained cytoplasms were regarded as immature types (22). An examina tion by 'H-thymidine autoradiography was performed on cells from 5 CSF specimens (1 case of zoster meningitis, 3 cases of radiculomeningitis after tick bite) in the different studies (7).…”

Section: Cytological Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Zoster Meningitis and Radiculomeningitis after Tick Bite

Shoji¹,

Dommasch²

1979

Eur Neurol

View full text Add to dashboard Cite

Cytological changes in 9 samples of cerebrospinal fluid (CSF) from 5 patients with zoster meningitis and 12 samples from 5 patients with radiculomeningitis after tick bite were examined. 5 days after the onset of the skin eruption, the CSF cells in zoster meningitis consisted of many mononuclear blast forms – large lymphocytes and ‘immature’ plasma cells. 11–15 days after the onset of the skin rash, they were replaced by small lymphocytes, some ‘mature’ plasma cells and monohistiocytes. In radiculomeningitis after tick bite, however, the CSF cells examined 10–21 days after the onset of radicular pain consisted of many large lymphocytes, immature plasma cells and a few neutrophils. From these findings, it might be suggested that the acute meningeal reaction of zoster meningitis subsides within about 1 week after the onset of the skin rash, but that of radiculomeningitis after tick bite continues at least for 2–3 weeks after the onset of radicular pain.

show abstract

“…However, plasma cells may be seen in CSF in nonmyelomatous conditions, such as several infectious and noninfectious inflammatory diseases of the central nervous system. 33,40 Immunocytochemical techniques are very useful for the identification of monoclonality of plasma cells and for the diagnosis of myeloma with cavitary involvement. 35 The neoplastic plasma cells can be best identified by the presence of monoclonal immunoglobulins in their cytoplasm, 35 as in our case and eight prior cases with meningeal myeloma, 4,9,17,21,23,31,38,39 but in two of them, immunocytochemistry was performed only postmortem.…”

Section: Volume 40 Number 3/may-june 1996mentioning

confidence: 99%