The driving methods for a liquid crystal lens with a rectangular aperture and four applied voltages are discussed. The properties of the liquid crystal lens can be controlled by amplitudes, phases, and frequencies of the voltages. Three driving methods, including the amplitude method, phase method, and constant voltage method, are used to tune the focal length. The advantage of these methods is that the effective voltage in the aperture center can be controlled to be greater than the liquid crystal threshold voltage without applying a bias voltage. It is found that the constant voltage method to tune the lens by the phases and the amplitudes of the four voltages in sync keeping a constant voltage in the aperture center leads to lower optical aberrations and shorter response time.