The Possible Protective Role of Powder Cuttlefish Bone, Crabshell and Eggshell on Osteoporotic Rats

Abstract

Bone mass declines alongside maturing, particularly for ladies after menopause as a result of diminishing estrogen emission together with low calcium consumption. This examination was directed to examine the impact of powdered cuttlebone, crab shell and eggshell, on female rats with induced osteoporosis. Fifty adult female albino rats, of (200 ± 10 g) were haphazardly divided into five groups, the first group, negative control group (-ve) fed on basal diet only, the other four groups (10 rats each) were fed on basal diet containing 100 mg prednisone acetate as source of glucocorticoid/ kg diet to induce osteoporosis for two weeks. One group of them was selected as a positive control group, the other three groups were fed on prednisone acetate diets containing powder of cuttlebone, crabshell and eggshell, at the level of 2.5% individually. Blood samples and femur bones were gathered for measure both serum and bone markers of osteoporosis. The results indicated that, supplementation with powder of cuttlebone, crabshell and eggshell significantly (P<0.05) increase of Ca and P in serum of osteoporotic rats. There were a significant increment in serum free thyroxin (T4) and a significant decrease in parathyroid hormone (PTH). Femur bone mineral content (BMC) and bone mineral density (BMD) were likewise increased as compared to positive control group. In addition, liver functions were significantly (P<0.05) improved compared to the positive control group, while serum lipid profiles were significantly decreased. These results recommend that sustaining postmenopausal rats with osteoporosis on diets supplemented with powder of cuttlebone, crab shell and eggshell instigated an enemy of osteoporotic impact. This impact may be due to upgrade of bone arrangement and direction of some metabolic hormones which control calcium. Therefore, it could be recommended using powder of cuttlebone, crabshell and eggshell for postmenopausal women suffering from osteoporosis.

Characterization and Potential of Enhancing Bone Regeneration Using Raw Cuttlebone Aragonite Nanoparticles: In Vitro and In Vivo Studies.

“…This result is in accordance with a previous result that showed that rats subjected to the administration of cuttlefish bone powder showed significant increase in serum calcium and phosphorus and this could be attributed to an expanded osteoblastic movement, consequently improving bone development. 37 The increase in the bone formation and healing process due to ASDJ Ain Shams Dental Journal cuttlebone extract application has been confirmed previously in a study that measured osteoblasts formation by histochemical examination using Hematoxylin and eosin staining and proved that the higher production of osteoblasts revealed their higher proliferative activity. 38 Relating all the characterization tests for CBN especially the cytotoxicity and ALP activity can act as a fundamental interpretation basic for the histological findings of the experimental study.…”

Impact of Mollusca by-Products as a Natural Source of Calcium on the Quality of Rusk

“…Also, Galal (2019) found that the Ca content of two different cuttlebones (from Korea and India) were 22341.4 and 22233.6 mg / 100 g, respectively. In addition, Negm (2018) reported that the mineral content of cuttlebone powder was (26.16, 14.24, 7.50 and 2.42 mg/g dry matter) for Ca, K, Mg, and P, respectively. Meanwhile, the results in the same Table showed that oyster shells exhibited the highest sodium (Na) content of 534.08 mg/100g powder followed by cuttlebone and donax powders.…”

“…Olgun et al, (2015) reported that the mineral content of the oyster shell was 320.9 calcium, 1.09 phosphorus, and 9.08 g/kg magnesium. Negm, (2018) indicated that cuttlebone contains a high Ca content, and low content of other elements such as K, Mg, and P with values of 26.16, 14.24, 7.50 and 2.42 mg/g , respectively.…”

Fundamental knowledge for nurses

“…[22][23] many clinical steps are proposed (Table 1). In summary, different types of nursery, such as suicide prevention [39][40][41][42][43] bone diseases [44][45][46][47][48][49][50] metabolic diseases [51][52][53][54][55][56][57] neural and mental diseases 58-60 emergence 61-65 cancer 66-70 herbal medicine [71][72][73][74][75][76][77] and so on are reiterated. They can promote their practice by fundamental medical knowledge promotion (Table 2).…”