The posterior capsule and phacoemulsification

Clinical study of Nd Yag Laser in the treatment of Posterior Capsular Opacification after Cataract Surgery

“…The finding that PCO results from lens epithelial cells proliferating onto posterior capsule at the site of apposition of anterior capsule flaps, explains the inadequacy of polishing the capsule at surgery to delay onset or reduce the frequency of late capsular opacification, because polishing PC cannot remove the epithelial cells from the anterior capsule flaps 17 .…”

Efficacy ofCOX‐2 inhibitors in controlling inflammation and capsular opacification after phacoemulsification cataract removal

“…Highly effective immediate restoration of vision gradually declines due to the development of posterior capsule opacification (PCO, secondary cataract, after cataract). In 50% or more human patients and up to 100% of canine patients, PCO results in loss of a clear visual axis. In addition, histopathologic and clinical studies have shown that canine patients can develop a low level of persistent inflammation in the eye for many months post cataract extraction .…”

Inhibition of Posterior Capsule Opacification by 5-Fluorouracil in Rabbits

“…Extracapsular cataract extraction (ECCE) with implantation of a posterior chamber intraocular lens has become in recent years the most popular technique for cataract sur gery [1], However, one of its most frequent complications is posterior capsule opacifica tion (PCO) which appears in as much as 50% of the cases between the 3rd and 5th year postoperatively [2][3][4], PCO is caused by mi gration, proliferation, and metaplasia to fi broblasts of the epithelial cells of the anterior capsule on the posterior capsule surface [5,6]. Its direct consequence is the need for a posterior capsulotomy which is not free from the risk of complications [7,8],…”