The Predictive Value of Barthel Score, Sequential Organ Failure Assessment Score, and D-Dimer in the 28-Day Prognosis of Patients with Non-ST Elevation Myocardial Infarction: A Retrospective Study of 358 Patients

Dai, GuiYing; Wang, Junyu; Gao, Fengli; Liu, Wenhong; Li, Ping; Wei, Bing; Yang, Jing

doi:10.2147/ijgm.s379628

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…SOFA scores are an important part of sepsis-3 criteria. Previous studies have reported that SOFA scores are a useful early prognostic marker for predicting 28-day mortality in sepsis patients [19], as well as the 28-day mortality in acute non-ST elevation myocardial infarction patients [20]. Therefore, in the present study, we combined SOFA scores with in ammatory biomarkers values to predict the mortality of sepsis patients with CAD.…”

Section: Discussionmentioning

confidence: 97%

Neutrophil-to-Lymphocyte ratio, Monocyte-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio associated with 28-day mortality in sepsis patients with coronary artery disease

Chen

Yuan

et al. 2023

Preprint

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Background High Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), Platelet-to-Lymphocyte Ratio (PLR) were associated with worse prognosis of sepsis patients, but the relationship between NLR, MLR, PLR and mortality in sepsis patients with coronary artery disease (CAD) remains unclear. The purpose of this study was to explore the association between NLR, MLR, PLR and 28-day mortality in sepsis patients with CAD, and to evaluate diagnostic accuracy combining sequential organ failure assessment (SOFA) scores.Methods Our study was based on cross-sectional and 28-day in-hospital data obtained from the MIMIC-III database between 2008 and 2012. Clinical characteristics and laboratory test data has been collected from hospitalization record. The relationship between NLR, MLR, PLR and 28-day mortality in sepsis patients with CAD was examined using the Cox proportional hazards model. We applied Receiver operating characteristic (ROC) analysis for predicting 28-day mortality in sepsis patients with CAD by combining NLR, MLR and PLR with the sequential organ failure assessment SOFA scores.Results This study included 984 sepsis patients with CAD in total. Sepsis patients with CAD who had high NLR, MLR, and PLR had a higher risk of 28-day mortality. (All P < 0.05). The AUCs of NLR, MLR, PLR, and SOFA score were 0.609, 0.606, 0.594 and 0.676, respectively. Combining NLR, MLR, and PLR with SOFA scores increased the diagnostic accuracy of predicting 28-day mortality (AUC: 0.703).Conclusion High NLR, MLR and PLR were associated with 28-day mortality in sepsis patients with CAD.

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Section: Discussionmentioning

confidence: 97%

Neutrophil-to-Lymphocyte ratio, Monocyte-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio associated with 28-day mortality in sepsis patients with coronary artery disease

Chen

Yuan

et al. 2023

Preprint

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The prognostic value of Barthel index for mortality in older patients with hypertrophic cardiomyopathy: Longitudinal Prediction Study

Song,

Zheng,

et al. 2024

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Background Impairment of activities of daily living (ADL), assessed according to the Barthel index (BI) score, is common and associated with poor outcomes in older population. The association between impairment of ADL and the prognosis in older patients with hypertrophic myocardiopathy (HCM) has not been well studied. Methods A total of 351 older patients with HCM in our center between January 2014 and December 2017 were enrolled in this study. The clinical profile and outcomes were evaluated. According to BI score, patients were divided into three groups: total/severe dependency in ADL (≤ 60) vs. moderate dependency (65–90) vs. slight dependency/independency (95–100). Kaplan-Meier analysis and Multivariable Cox regression models were conducted to test the prognostic value of BI in older patients with HCM. Results 27(8%) patients with BI ≤ 60 vs. 48(14%) patients with BI 65–90 vs. 276(78%) patients with BI 95–100. During a follow-up of 65 ± 21 months, 72 patients died (50 cardiovascular deaths). The 5-year survival free from all-cause mortality was 48.2% (95% CI 28.7–65.2%) in patients with BI ≤ 60, 62.0% (95% CI 46.7–74.2%) in patients with BI 65–90, and 89.7% (95% CI 85.5–92.8%) in patients with BI 95–100. The 5-year survival free from cardiovascular mortality was 54.4% (95% CI 33.7–71.1%) in patients with BI ≤ 60, 69.0% (95% CI 53.2–80.4%) in patients with BI 65–90, and 94.0% (95% CI 90.4–96.3%) in patients with BI 95–100. BI was a significantly associated with all-cause mortality (hazard ratio 0.978, 95% CI 0.968–0.989, P<0.001) and cardiovascular mortality (hazard ratio 0.975, 95% CI 0.963–0.987, P<0.001). Conclusions Impairment in ADL was associated with poor outcomes in older patients with HCM, routine assessment of ADL using BI may help in decision-making and health care planning for older patients with HCM.

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The Predictive Value of Barthel Score, Sequential Organ Failure Assessment Score, and D-Dimer in the 28-Day Prognosis of Patients with Non-ST Elevation Myocardial Infarction: A Retrospective Study of 358 Patients

Cited by 2 publications

References 16 publications

Neutrophil-to-Lymphocyte ratio, Monocyte-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio associated with 28-day mortality in sepsis patients with coronary artery disease

Neutrophil-to-Lymphocyte ratio, Monocyte-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio associated with 28-day mortality in sepsis patients with coronary artery disease

The prognostic value of Barthel index for mortality in older patients with hypertrophic cardiomyopathy: Longitudinal Prediction Study

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