The preparation, characterization, and crystal and molecular structure of oxobis(ethan-1,2-dithiolato-S,µS′)technetium(V)oxo(ethan- 1,2-dithiolato-S,S′)technetium(V) [(TcO)₂(SCH₂CH₂S)₃]. A Tc(V) compound containing metal—sulfur—metal bridges

Abstract

The preparation, characterization, and crystal and molecular structure of oxobis(ethan-1,2-dithiolato-S,pSr)technetium(V)oxo(ethanl,2-dithiolato-S,Sr)technetium(V) [(TCO)~(SCH~CH~S)~]. A Tc(V) compound containing metal-sulfur-metal bridgesA. DAVISON 319 (1985). As a result of an investigation undertaken to evaluate the acetamidomethyl group (-CH,NHCOCH,) as a water-solubilizing protecting group for thiolate ligands, a new type of oxotechnetium(V) complex was prepared. The compound oxobis(ethan- [Traduit par le journal]

Synthesis and characterization of complexes of the {ReO}3+ core with SNS and S donor ligands

“…The Re=O bond length is found to be 1.699(5) Å well within the range observed for other {ReO} 3+ complexes [24,31,[41][42][43][44][45][46][47][48][49][50][51][52]. Likewise, the Re-N bond length [Re-N(1)= 2.208(6) Å] is typical for the Re-N amine single bond in which the nitrogen atom exhibits sp 3 hybridization [24,31,[41][42][43][44][45][46][47][48][49][50][51][52]. However, in the case of the metal-sulfur bond lengths, those in the equatorial plane are similar [ [24,31,[41][42][43][44][45][46][47][48][49][50][51][52].…”

“…Likewise, the Re-N bond length [Re-N(1)= 2.208(6) Å] is typical for the Re-N amine single bond in which the nitrogen atom exhibits sp 3 hybridization [24,31,[41][42][43][44][45][46][47][48][49][50][51][52]. However, in the case of the metal-sulfur bond lengths, those in the equatorial plane are similar [ [24,31,[41][42][43][44][45][46][47][48][49][50][51][52]. The rhenium atom is situated 0.0817 Å, above the equatorial plane of the trigonal bipyramid in the direction of the monothiol.…”

Synthesis of sulfido and oxo complexes of technetium(V) and rhenium(V) containing dithiolato and hydrotris(1-pyrazolyl)borato ligands. Crystal structures of dimeric bis(.mu.-ethane-1,2-dithiolato)bis(ethene-1,2-dithiolato)technetium(IV) and [hydrotris(1-pyrazolyl)borato](ethane-1,2-dithiolato)oxorhenium(V)

“…According to the literature, the reaction of 2 equiv of H2edt with [RevOX4]~(X = Cl, Br) in THF affords the orange complex [RevO(edt)2]~by ligand exchange.32 The same product could be obtained by reduction of [Re04]-with NaBH4 in the presence of H2edt.32 Similarly, the ligand-exchange reaction of H2edt on [TcvOCl4]-or [TcvO(gluconate)]~i n alkaline water/ EtOH mixtures or the reduction of [Tc04]by sodium dithionite in the presence of excess of H2edt yields the orange [TcvO(edt)2]complex.32-34 A stable side product, namely the dinuclear complex [(TcvO)2(edt)3], has been also been reported. 27 A common feature of these reactions is that they give rise to complexes containing the [M=0]3+ core (M = Tc, Re) without formation of the isoelectronic [M=S]3+ core. In contrast, treatment of the complex [ReIVCl6]2-with excess of H2edt, in the presence of Et3N, yields the red-brown compound [RevS(edt)2]containing a terminal rhenium-sulfido group.9 It was proposed that the source of sulfido ligands in this reaction is the dithiolate itself, which should undergo a degradation process with the concomitant formation of ethylene as stable byproduct.9 In the attempt to prepare the analogous technetium-sulfido complex [TcvS(edt)2]-, we used to same synthetic approach by treating a suspension of [Tc,vCl6]2-in MeOH with excess H2edt, in the presence of Et3N as deprotonating agent.…”

Harvard-MIT research program in short-lived radiopharmaceuticals. Final report

“…Results [1977][1978][1979][1980][1981][1982][1983][1984][1985][1986][1987][1988][1989] Studies in Technetium Chemistry -to facilitate the design of radiopharmaceuticals first identification and characterization of oxotechnetium(V) complexes isolated from aqueous solution elucidation of the systematics in technetium complexation first application of high resolution field desorption mass spectroscopy to the structure of these complexes design and synthesis of new agents for heart, brain, and kidney imaging based on the chemistry of the element; n.b. isonitriles for cardiac imaging with SPECT development of new classes of cationic and neutral complexes determination that the uptake of Tc(AcAc), complexes by the brain has a maximum that depends on lipophilicity…”