The preparation of thiophenes. III. From aromatic compounds and carbon disulphide

Preparation of Highly Functionalised Benzofurans from ortho‐Hydroxyphenones and Dichloroethylene: Applications and Mechanistic Investigations

“…These involve ring fragmentations [25][26][27] and oxidative processes. [28][29][30] Recently, we reported some preliminary results on a novel benzofuran synthesis, [31] based upon our previous incursion into the largely unexplored Z-chloromethylene ketal chemistry. [32] Thus, starting from a variety of o-hydroxyphenones 9 and 1,1-dichloroethylene, a range of chloromethylene furans 10 could be obtained in high yield.…”

“…At this stage, it is important to point out that several alternative, though less general, methodologies14–24 have also been described. These involve ring fragmentations25–27 and oxidative processes 28–30…”