The prescription of methadone for opiate dependence in Australia, 1985‐1991

Abstract

ObjectiveTo describe the rates and patterns of prescription of methadone for opiate dependence in Australia from 1985 to 1991. DesignData on the numbers of Australians prescribed methadone in States and Territories were used to calculate prevalence rates of prescription of methadone. ResultsIn 1985, Queensland had the highest rate of prescription of methadone. After the establishment of the National Campaign Against Drug Abuse, rates increased in most jurisdictions. Assessment procedures and prescribing practices, such as private prescription of methadone, appear to have markedly affected rates of prescription in some States. ConclusionLarge differences in rates of methadone prescription have occurred in Australian States and Territories. There are inadequate data to explain how rates of prescription are related to the prevalence of opiate use. Investigations of prevalence of injecting opiate use, demand for treatment and clinic practices are needed to explain these patterns fully.

Fluvoxamine-Methadone Interaction

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Recently approved in Australia for the management of major depression and obsessive-complusive disorder, fluvoxamine has a different profile of drug interactions to those involving other selective serotonin re-uptake inhibitors (SSRIs) [1,2]. Methadone is widely prescribed in Australia as a pharmacological strategy for the management of opioid dependence, although regional prescribing patterns are variable [3]. In addition, methadone is also prescribed as an analgesic for the treatment of chronic pain.

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