The Present Status of Surgery in the Treatment of Carcinoma of the Hypopharynx and Cervical Oesophagus

DNA measurements for monitoring chemotherapy in advanced head and neck carcinomas

“…[15][16][17][18] For the past 15 years, several explanations for this is the fact that currently, there is no objective tool to predict good or bad response to c h e m~t h e r a p y .~~-~~ Quantitative DNA measurements have demonstrated prognostic significance in head and neck carcinomas in order to predict the overall survival…”

“…Conventional treatment strategies for patients with advanced head and neck squamous cell carcinomas consists of surgery and postoperative radiotherapy. [15][16][17][18] For the past 15 years, several The changes in the DNA data in the responder group are evident after the first course of chemotherapy, which is highly significant (p = 0.001 for mean DNA content, p = 0.001 for 2c DI, p = 0.001 for 5c ER, and p = 0.002 for DNA-MG). In the nonresponders, only minor changes occur after the first course of Chemotherapy.…”