The prevalence and predictors of pre-hypertension and hypertension in Kherameh cohort study: a population based study on 10,663 persons in south of Iran

Rezaianzadeh, Abbas; Jafari, Fatemeh; Sadeghi, S. E.; Rahimikazerooni, Salar

doi:10.1038/s41371-020-0330-8

Cited by 19 publications

(21 citation statements)

References 38 publications

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“…In this study, smoking was negatively correlated with hypertension. This trend has been also observed in other cohort observations [ 13 ]. Researchers have found that smoking is significantly correlated with masked hypertension [ 14 ], which often underestimates the role of smoking in hypertension.…”

Section: Discussionsupporting

confidence: 89%

The Prevalence of Hypertension in the Population without Awareness of the Disease: Data from a Rural Town of Shandong Province, China

Wei

Dong

Wang

et al. 2021

International Journal of Hypertension

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Objective. To understand the prevalence of hypertension in the population without awareness of hypertension in a rural area, a cross-sectional study was carried out. Methods. Blood pressures were measured in residents over 60 years during the National Basic Public Health Service project carrying on in a rural town of Shandong province. Combined with detail information of the hypertension disease history, the status of prevalence of hypertension was calculated. Basic information and clinical laboratory examinations were analyzed with Student’ t or t’ or chi-square test for univariate analysis. Multinomial logistic analysis was used in exploring multiple variables. Results. According to the individual history and blood pressure levels, the awareness rate of hypertension in the population over 60 years old was 50.3% (1285/2554, 95% CI: 48.3–52.3%). The prevalence of hypertension was 55.1% (1270/2304, 95% CI: 53.1–57.2%) in the population without awareness of hypertension, in which the proportion of stage 1 hypertension was 58.8% (747/1270), stage 2 hypertension was 28.9% (367/1270), and stage 3 hypertension was 12.3% (156/1270). The prevalence of hypertension in men was 54.4% (611/1124, 95% CI: 51.4–57.3%), which was almost the same as that in women (55.8%, 659/1180, 95% CI: 53.0–58.7%) (X2 = 0.515, P = 0.473 ). The prevalence of hypertension increased with age (X2trend = 11.848, P = 0.001 ). Age, BMI, total cholesterol, triglyceride, and drinking rate were positively correlated with the prevalence of hypertension, that is, the higher the level of these factors, the higher the prevalence of hypertension; on the contrary, LDL and smoking rate might be negatively correlated with the prevalence of hypertension, which means, the higher the prevalence of hypertension, the lower the level of these two indicators. Binary and multinominal logistic results showed that age, BMI, and drinking had stronger effects on the higher blood pressure level. Conclusions. The awareness rate of hypertension among the elderly in a rural area needs to be further improved. In the prevention and control of hypertension, close attention should be paid to the group of elder, high BMI index, high levels of total cholesterol and triglyceride, and drinking habits.

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Section: Discussionsupporting

confidence: 89%

The Prevalence of Hypertension in the Population without Awareness of the Disease: Data from a Rural Town of Shandong Province, China

Wei

Dong

Wang

et al. 2021

International Journal of Hypertension

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“…Dyslipidemia was defined as cholesterol levels above 200 mg/dL or triglyceride serum levels above 150 mg/dL. Additionally, diabetes was defined as a history of diabetes or fasting blood sugar above 126 mg/dL [ 21 , 22 ]. The participants’ average physical activity was also evaluated during the past year.…”

Section: Measurementmentioning

confidence: 99%

The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran

Baeradeh

Johari‬

Moftakhar

et al. 2022

BMC Cardiovasc Disord

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Background The prevalence of cardiovascular disease (CVD) is rapidly increasing in the world. The present study aimed to assess the prevalence and Predictors factors of CVD based on the data of Kherameh cohort study. Methods The present cross-sectional, analytical study was done based on the data of Kherameh cohort study, as a branch of the Prospective Epidemiological Studies in Iran (PERSIAN). The participants consisted of 10,663 people aged 40–70 years. CVD was defined as suffering from ischemic heart diseases including heart failure, angina, and myocardial infarction. Logistic regression was used to model and predict the factors related to CVD. Additionally, the age-standardized prevalence rate (ASPR) of CVD was determined using the standard Asian population. Results The ASPR of CVD was 10.39% in males (95% CI 10.2–10.6%) and 10.21% in females (95% CI 9.9–10.4%). The prevalence of CVD was higher among the individuals with high blood pressure (58.3%, p < 0.001) as well as among those who smoked (28.3%, p = 0.018), used opium (18.2%, p = 0.039), had high triglyceride levels (31.6%, p = 0.011), were overweight and obese (66.2%, p < 0.001), were unmarried (83.9%, p < 0.001), were illiterate (64.2%, p < 0.001), were unemployed (60.9%, p < 0.001), and suffered from diabetes mellitus (28.1%, p < 0.001). The results of multivariable logistic regression analysis showed that the odds of having CVD was 2.25 times higher among the individuals aged 50–60 years compared to those aged 40–50 years, 1.66 folds higher in opium users than in non-opium users, 1.37 times higher in smokers compared to non-smokers, 2.03 folds higher in regular users of sleeping pills than in non-consumers, and 4.02 times higher in hypertensive individuals than in normotensive ones. Conclusion The prevalence of CVD was found to be relatively higher in Kherameh (southern Iran) compared to other places. Moreover, old age, obesity, taking sleeping pills, hypertension, drug use, and chronic obstructive pulmonary disease had the highest odds ratios of CVD.

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“…This should not be attributed to the urban residency of our study population, as no significant difference was observed between urban and rural residents as to the HTN prevalence 11. Kherameh cohort study labelled 27.7% of its study population as hypertensive 32. Relatively higher BP was reported in the Fasa cohort study in 2020 10.…”

Section: Discussionmentioning

confidence: 57%

“… 11 Kherameh cohort study labelled 27.7% of its study population as hypertensive. 32 Relatively higher BP was reported in the Fasa cohort study in 2020. 10 The authors have reported a prevalence of 16.1% for stage 1 HTN and 17.9% for stage 2.…”

Section: Discussionmentioning

confidence: 87%

Can anthropometric indices predict the chance of hypertension? A multicentre cross-sectional study in Iran

et al. 2022

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ObjectivesThis study aims to assess the prevalence of hypertension (HTN), and determine the relationship between HTN and anthropometric indices including fat distribution, body mass index (BMI), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) in Shiraz Heart Study.SettingIn this cross-sectional study, subjects were enrolled in 25 clinics in Shiraz. I.R. Iran between 2019 and 2021.ParticipantsA total number of 7225 individuals were selected, aged between 40 and 70 years of whom 52.3% were female. Among the people living in Shiraz, individuals living far from clinics, cases of mental or physical disabilitiy and documented cardiovascular diseases were excluded.Primary and secondary outcome measuresPrimary outcome: The association of body composition, WHR, WHtR and BMI with HTN.Secondary outcome: The sensitivity and specificity of the WHtR for the prediction of HTN.ResultsHTN prevalence was 19.3%. Obesity prevalence was estimated to be 28.5%. WHR and lean body mass showed a significant association with HTN (p<0.05). Receiver operating characteristic for WHtR yielded an area under the curve of 0.62 (95% CI 0.61 to 0.64) and 0.63 (95% CI 0.62 to 0.65) for males and females, respectively. The optimal threshold value yielded 0.54 in men and 0.61 in women. The sensitivity was 72.3% and 73.9% in women and men, with specificity of 48.4% and 44.3%, respectively.ConclusionHTN had a meaningful association with all the noted anthropometric indices. WHtR performed well as a predictor of HTN.

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The prevalence and predictors of pre-hypertension and hypertension in Kherameh cohort study: a population based study on 10,663 persons in south of Iran

Cited by 19 publications

References 38 publications

The Prevalence of Hypertension in the Population without Awareness of the Disease: Data from a Rural Town of Shandong Province, China

The Prevalence of Hypertension in the Population without Awareness of the Disease: Data from a Rural Town of Shandong Province, China

The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran

Can anthropometric indices predict the chance of hypertension? A multicentre cross-sectional study in Iran

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