The prevalence and risk factors for osteoporosis among 18- to 49-year-old Turkish women

Pınar, Gül; Kaplan, Sena; Pınar, Tevfik; Akalın, Ayşe; Abay, Halime; Akyol, Mesut; Sezer, Nebahat; Akkuş, Selami; Sariyildiz, Salim; Dinc, RN Semra

doi:10.1080/03630242.2016.1243604

Cited by 9 publications

(7 citation statements)

References 34 publications

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“…Consanguinity was present in 48% of the patients in our study. This rate proves to be more than double the rate of consanguinity in Turkey (20%) 20 . Furthermore, a sibling of one of our patients died with similar symptoms.…”

Section: Discussionsupporting

confidence: 52%

Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis

Hızal

Polat

Gürsoy

et al. 2021

Pediatric Pulmonology

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Objectives To evaluate the risk factors of recurrent pulmonary exacerbation and poor prognosis in children with idiopathic pulmonary hemosiderosis (IPH). Methods In this multicenter study, 54 patients with a diagnosis of IPH were included. Medical records were retrospectively reviewed from three tertiary care hospitals between 1979 and 2019. Also, current information and the long‐term progress of patients was determined by contacting the families by telephone. Results A total of 54 children were included. The median age of onset of symptoms was 4.5 years (3 months to 15.8 years). The median time from onset to diagnosis was 0.9 years (0.25 months to 12 years). The mean number of recurrent episodes per child in the recurrence‐positive group was 3.55 (1–15). Univariate analysis demonstrated that patients presenting with hypoxia or requiring transfusion at the time of presentation had significantly more recurrence episodes (p = .002). Multivariate analysis showed that the presence of hypoxia at the time of initial presentation was a significant independent predictor of recurrent episodes (p = .027). The median follow‐up was 3.3 years (0.75 months to 27 years). There was a significant relationship between the presence of hypoxia, transfusion history, antinuclear antibody positivity, and elevated transaminases at the time of initial evaluation and treatment response. Conclusions The present study provides substantial information regarding factors that may affect recurrent exacerbations and prognosis in children with IPH. Demonstrating hypoxia as an independent risk factor in recurrence episodes could guide physicians in the planning of treatment strategies.

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Section: Discussionsupporting

confidence: 52%

Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis

Hızal

Polat

Gürsoy

et al. 2021

Pediatric Pulmonology

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“…This rate proves to be more than the double the rate of consanguinity in Turkey (20%). 19 Furthermore, a sibling one of our patient's died with similar symptoms. Our result, in line with those of previous studies, indicates that genetics might play a role in the underlying mechanisms of IPH.…”

Section: Discussionmentioning

confidence: 51%

Risk Factors for Recurrent Pulmonary Exacerbation in Idiopathic Pulmonary Hemosiderosis

Hızal

Polat

Gürsoy

et al. 2020

Preprint

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Objectives: To evaluate the risk factors of recurrent pulmonary exacerbation and poor prognosis in children with idiopathic pulmonary hemosiderosis (IPH). Methods: In this multicenter study, 54 patinets with diagnosis of IPH included. Medical records were retrospectively reviewed from three tertiary care hospitals between 1979 and 2019. Also, current information and the long-term progress of patients was determined by contacting the families by telephone. Results: A total of 54 children were included. The median age of onset of symptoms was 4.5 ± 3.8 years. The median time from onset to diagnosis was 0.9 years ± 2.2. The mean number of recurrent episodes per child in the recurrence-positive group was 3.55 (1-15). Univariate analysis demonstrated that patients presenting with hypoxia or requiring transfusion at the time of presentation had significantly more recurrence episodes (P=0.002). Multivariate analysis showed that the presence of hypoxia at the time of initial presentation was a significant independent predictor of recurrent episodes (P=0.027). The median follow-up was 3.3 ± 4.8 years (0.75 months-27 years). There was a significant relationship between the presence of hypoxia, transfusion history, ANA positivity, and elevated transaminases at the time of initial evaluation and treatment response. Conclusions: The present study provides important information on the clinical course and outcome of pediatric IPH, and substantial information regarding factors that affect recurrent exacerbations and prognosis. Demonstrating of hypoxia as an independent risk factor in recurrence episodes could be guide physicians in the planning of treatment strategies.

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“…A study in Turkey showed that women between the ages of 18–49 who smoke, have fair skin, or have a family history of osteoporosis are at higher risk for osteoporosis [ 7 ]. The clinical symptoms of osteoporosis in old age include decreased body height, dowager’s hump or kyphosis, bone fracture and respiratory impairment [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis

et al. 2021

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Background Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment and medical care. Providing a comprehensive picture of the prevalence of osteoporosis globally is important for health policymakers to make appropriate decisions. Therefore, this study was conducted to investigate the prevalence of osteoporosis worldwide. Methods A systematic review and meta-analysis were conducted in accordance with the PRISMA criteria. The PubMed, Science Direct, Web of Science, Scopus, Magiran, and Google Scholar databases were searched with no lower time limit up till 26 August 2020. The heterogeneity of the studies was measured using the I2 test, and the publication bias was assessed by the Begg and Mazumdar’s test at the significance level of 0.1. Results After following the systematic review processes, 86 studies were selected for meta-analysis. The sample size of the study was 103,334,579 people in the age range of 15–105 years. Using meta-analysis, the prevalence of osteoporosis in the world was reported to be 18.3 (95% CI 16.2–20.7). Based on 70 studies and sample size of 800,457 women, and heterogenicity I2: 99.8, the prevalence of osteoporosis in women of the world was reported to be 23.1 (95% CI 19.8–26.9), while the prevalence of osteoporosis among men of the world was found to be 11.7 (95% CI 9.6–14.1 which was based on 40 studies and sample size of 453,964 men.). The highest prevalence of osteoporosis was reported in Africa with 39.5% (95% CI 22.3–59.7) and a sample size of 2989 people with the age range 18–95 years. Conclusion According to the medical, economic, and social burden of osteoporosis, providing a robust and comprehensive estimate of the prevalence of osteoporosis in the world can facilitate decisions in health system planning and policymaking, including an overview of the current and outlook for the future; provide the necessary facilities for the treatment of people with osteoporosis; reduce the severe risks that lead to death by preventing fractures; and, finally, monitor the overall state of osteoporosis in the world. This study is the first to report a structured review and meta-analysis of the prevalence of osteoporosis worldwide.

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The prevalence and risk factors for osteoporosis among 18- to 49-year-old Turkish women

Cited by 9 publications

References 34 publications

Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis

Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis

Risk Factors for Recurrent Pulmonary Exacerbation in Idiopathic Pulmonary Hemosiderosis

The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis

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