The Prevalence and Topography of Multiple Level Obstruction in Cases of Obstructive Sleep Apnea

Abstract

of AHI of both sleep studies were significantly correlated (r = 0.762). There was also a high correlation between the values of the following variables: minimum oxygen saturation (r = 0.842, p<0.001), oxygen saturation <90% (r = 0.799, p <0.001), and mean heart frequency (r = 0.951, p <0.001). The analysis which used ROC curve to test the diagnostic efficiency of Watch PAT concluded that the area under the curve could reach 0.727 if the threshold of 12 events/hour was used as the cut-off point in this study with a sensitivity of 96.2% and a specificity of 60%. When analyzing the severe cases of obstructive sleep apnea (OSA) (AHI ≥ 30 events/hour), the area under the curve was 0.846 with a sensitivity of 77.8% and a specificity of 86.4%.Conclusions: Watch PAT tends to overestimate the AHI when compared with PSG, especially for mild OSA. The Watch PAT is an alternative method that is reliable and highly sensitive for the diagnosis of SDB.Objectives: Uvulopalatopharyngoplasty (UPPP) has been described as an option for treating obstructive sleep apnea syndrome (OSAS), with variable success rates. The main purpose of this study is to correlate UPPP success to craniofacial bony structure and orofacial muscle function.Methods: Prospective longitudinal study in a tertiary clinical center. Fifty-four patients who underwent UPPP in the last 7 years were followed, and UPPP succeeded or failed based on the results of pre-operative and post-operative polysomnography. Clinical variables' body mass index (BMI), age, and preoperative apnea-hypopnea index (AHI)'s cephalometric measurements (craniofacial region and hyoid bone position), and muscle function variables (clinical protocol and tongue strength measures) were evaluated and compared between the groups (failure or success after UPPP). Results:The variables BMI, pre-operative AHI, and cephalometric measurements showed no influence on surgical success. The clinical muscle protocol was also similar between groups. However, the muscle strength of the anterior portion of the tongue was significantly greater in the group that showed surgical success compared to those with surgical failure. This movement is primarily performed by genioglossus muscle.Conclusions: OSAS is a multifactorial disease, and diagnostic symptom assessments should be individualized. In addition, special attention should be given to functional muscle alterations of the airways, because they might influence the evolution of the disease.Objectives: Determine the prevalence of multiple level obstruction and the frequency of their sites in cases of obstructive sleep apnea. Methods:The sample size of this descriptive cross sectional study was an inclusive sample including all patients presenting to the outpatient clinic of Suez Canal University Hospital, Ismaila Egypt complaining of snoring with or without obstructive sleep apnea (OSA) between January 1 and December 31. All patients were evaluated by Müller maneuver followed by polysomnography. Patients diagnosed with OSA were subjected to drug induced sleep endo...