The prevalence of allergic rhinitis and atopic markers in obstructive sleep apnea

Gadi, Ghadah; Wali, Siraj; Koshak, Emad A.; Al-Bar, Mohammad H.; Fida, Abdulkareem R.; Abdelaziz, Muntasir M.; Al-Noury, Khaled; Alama, Nabil

doi:10.1016/j.jegh.2016.06.001

Cited by 15 publications

(6 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The data collection tool comprised of two main domains. It was developed based on the commonly reported exposures in literature (participants’ characteristics) [12, 19, 20] and the 2016 ARIA guidelines that defined the AR disease characteristics [21]. The participants’ characteristics were the study exposures, which included the sex, age (years), body mass index (BMI), area of residence, occupation, the presence of chronic medical conditions, disease duration, family history, and smoking status.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia

et al. 2019

View full text Add to dashboard Cite

Background Despite allergic rhinitis (AR) being a highly prevalent disease, according to literature, it is often underdiagnosed or undertreated. Aim This study explored the disease characteristics of AR in the Saudi community and the non-conventional coping measures used to alleviate symptoms. Methods The study was a nationwide cross-sectional study, using a self-report electronic survey distributed via social media networks in 2018. The survey included an explanatory letter and consent. The sample size comprised 3,458 participants and 2,849 adults had at least one of the four signs of AR, i.e. watery-nose, sneezing, nasal obstruction, itchy nose, watery eyes, in the past year, not related to cold/flu. The outcomes of the study were the triggers, pattern, severity and the classification of AR (2016 ARIA guidelines) and coping measures. Descriptive statistics, univariate analytic statistics and binary logistic regression analyses were conducted. The P-value was considered statistically significant at <0.05. Results The leading reported trigger of AR was dust (74%, n = 2118), followed by pollen (17%, n = 477), mold (5%, n = 140) and fur (4%, n = 114). The prevalence of intermittent AR was (54%, n = 1,635), while that of persistent AR was (46%, n = 1,314). Almost one-third (34%, n = 959) complained of mild forms of AR, while others complained of moderate to severe forms (66%, n = 1890). The coping measures were mainly shower/humidification 368(12.9%) and herbal hot drinks 266(9.3%). Older participants (adj.OR = 1.3[1.1–1.5]) and overweight participants, (adj.OR = 1.2[1.1–1.4]) reported more persistent forms of rhinitis compared to their counter groups, (adj.P<0.001 and adj.P = 0.032) respectively. Female participants (adj.OR = 0.8[0.7–0.9]) had significantly milder forms of AR, in comparison to males, adj.P = 0.006. Conclusion This study presented the disease characteristics of self-reported AR and its associated factors in Saudi Arabia. Special attention should be paid to older age groups and overweight patients who reported persistent forms of AR. Males reported more severe and persistent forms of AR.

show abstract

Section: Methodsmentioning

confidence: 99%

“…Despite the spread of AR worldwide and in particular within high risk countries such as Saudi Arabia, there is a dearth of studies investigating disease characteristics and local coping measures [12]. Saudi Arabia is known for its frequent and periodic sandstorms in all seasons.…”

Section: Introductionmentioning

confidence: 99%

Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Learning problems and excessive daytime sleepiness were comparable between children with SDB, SDB+RT and RT. As allergy is also considered as a risk factor for SDB ( Gadi et al., 2017 ; Zheng et al., 2017 ), we compared allergic presentations across groups. Rhinitis and itchy eyes were more prevalent in children with adenotonsillar diseases compared to healthy controls (p=0.001 and p=0.041) but prevalence amongst children with either SDB, SDB+RT or RT (p=0.625) was similar.…”

Section: Resultsmentioning

confidence: 99%

Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies

Mateus

Seppanen

Gier

et al. 2022

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

BackgroundThe underlying pathogenesis of pediatric obstructive sleep disordered breathing (SDB) and recurrent tonsillitis (RT) are poorly understood but need to be elucidated to develop less invasive treatment and prevention strategies.MethodsChildren aged between 1- and 16-years undergoing adenoidectomy, tonsillectomy or adenotonsillectomy for SDB (n=40), RT alone (n=18), or both SDB and RT (SDB+RT) (n=17) were recruited with age-matched healthy controls (n=33). Total bacterial load and species-specific densities of nontypeable Haemophilus influenzae (NTHi), Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae and Moraxella catarrhalis were measured by qPCR in nasopharyngeal swabs, oropharyngeal swabs, adenoid and tonsillar tissue from children with SDB, SDB+RT and RT, and in naso- and oro- pharyngeal swabs from healthy children. A subset of tonsil biopsies were examined for biofilms using 16S rRNA FISH (n=3/group).ResultsThe 5 bacterial species were detected in naso- and oro- pharyngeal samples from all children. These species were frequently detected in adenotonsillar tissue (except S. aureus, which was absent in adenoids) from children with SDB, SDB+RT and RT. NTHi and S. aureus were observed in tonsils from 66.7-88.2% and 33.3-58.8% of children respectively. Similar total and species-specific bacterial densities were observed in adenotonsillar tissue from children with SDB, SDB+RT or RT. Nasopharyngeal and oropharyngeal swabs were more likely to have multiple bacterial species co-detected than adenotonsillar tissue where one or two targeted species predominated. Polymicrobial biofilms and intracellular bacteria were observed in tonsils from children with adenotonsillar disease.ConclusionsAntimicrobials, particularly anti-biofilm therapies, may be a strategy for managing children with SDB.

show abstract

“…Interestingly, patients with OSA have significantly more rhinitis than those people who do not suffer with OSA. 67 Medical interventions to improve nasal patency at night can improve sleep quality, however, improvements in specific objective sleep parameters have not yet been identified. 68 In those patients with an obstructive nasal passage, treatment of this condition has also been shown to improve the efficacy of CPAP and patients' compliance with it.…”

Section: Limitationsmentioning

confidence: 99%

Narrative review of contemporary treatment options in the care of patients with obstructive sleep apnoea

Ferguson

Magill

Kotecha

2017

Ther Adv Respir Dis

View full text Add to dashboard Cite

Snoring and obstructive sleep apnoea (OSA) are increasingly common conditions, and confer a significant health and socioeconomic burden. Furthermore, untreated OSA represents a significant mortality risk. Patients require careful assessment, including detailed clinical history and examination, sleep study and drug-induced sleep endoscopy (DISE). Although nasal continuous positive airway pressure (nCPAP) is the gold standard treatment for moderate and severe OSA, multidisciplinary team assessment is often required to develop the best treatment plan for an individual, especially when nasal CPAP is poorly tolerated. There is a wide range of medical and surgical treatment options, and following appropriate patient selection and assessment, a focused site-specific, often multilevel, intervention is indicated. There is an increasing body of evidence in the literature supporting these multilevel interventions and with agreement on standardized outcome measures more trials are likely to improve the robustness of these data further.

show abstract

The prevalence of allergic rhinitis and atopic markers in obstructive sleep apnea

Cited by 15 publications

References 27 publications

Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia

Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia

Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies

Narrative review of contemporary treatment options in the care of patients with obstructive sleep apnoea

Contact Info

Product

Resources

About