2018
DOI: 10.1016/j.diagmicrobio.2017.12.014
|View full text |Cite
|
Sign up to set email alerts
|

The prevalence of mcr -1 and resistance characteristics of Escherichia coli isolates from diseased and healthy pigs

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
13
1

Year Published

2018
2018
2024
2024

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 23 publications
(15 citation statements)
references
References 17 publications
0
13
1
Order By: Relevance
“…Apart from the wide genetic diversity, we detected a high prevalence of the mcr-1 gene (25%) in the commensal E. coli population. Although the study design and the host species were different, a similar alarming high frequency of mcr-1 was detected in E. coli from human and livestock sources in Thailand 23 and one study from China 24 . Overall, the high frequency of mcr-1 gene detected in this study is still the exception, and much higher than previously reported studies from Germany (3.8%) 25 , China (1% or less) and other countries 26 28 .…”
Section: Discussionmentioning
confidence: 80%
“…Apart from the wide genetic diversity, we detected a high prevalence of the mcr-1 gene (25%) in the commensal E. coli population. Although the study design and the host species were different, a similar alarming high frequency of mcr-1 was detected in E. coli from human and livestock sources in Thailand 23 and one study from China 24 . Overall, the high frequency of mcr-1 gene detected in this study is still the exception, and much higher than previously reported studies from Germany (3.8%) 25 , China (1% or less) and other countries 26 28 .…”
Section: Discussionmentioning
confidence: 80%
“…The 37 mcr-1 positive isolates recovered from PWD in Italy also showed genetically diverse pathotypes and all but one were resistant to ≥3 different antimicrobial families ( Curcio et al, 2017 ). Li et al (2017) found a higher prevalence of mcr-1 positie isolates among pathogenic E. coli from diseased pigs than from healthy pigs (45.1 versus 15.7%, P = 0.000); besides, resistance profiles of mcr-1 positive E. coli were more extensive than those of mcr-1 negative isolates. In our study, it is also of concern the finding of 11 out of the 65 mcr-1 isolates with MIC >32 mg/L for fosfomycin.…”
Section: Discussionmentioning
confidence: 85%
“…These are periods when pigs are most susceptible to getting diarrhoea from common pathogens such as post-weaning E. coli and salmonellosis. The use of colistin in pigs has been shown to lead to the development of a plasmid-mediated colistin-resistant gene in humans in China 7 25. Consequently, in 2018, DLD restricted the use of colistin for disease prevention in livestock, and farmers replaced it with halquinol.…”
Section: Discussionmentioning
confidence: 99%