The prevalence of polycystic ovaries in Chinese women with a history of gestational diabetes mellitus

Abstract

In the present study we aimed to define the prevalence of polycystic ovaries (PCO), using the revised ultrasound criterion, in Chinese women with previous gestational diabetes mellitus (GDM), as well as their associated clinical, hormonal and biochemical characteristics. Seventy Chinese women with previous GDM were recruited as the study group. The control group comprised women matched for age, parity and delivery year who had a normal oral glucose tolerance test during their index pregnancy. Two- and three-dimensional ultrasound scans were performed to study ovarian morphology and ovarian stromal blood flow. Anthropometric, hormonal and biochemical profiles were compared between women with and without ultrasound features of PCO. The prevalence of PCO in Chinese women was 23%. The group with a history of GDM had a higher but not statistically significant prevalence of PCO (34%). Compared with controls, they had significantly higher incidence of obesity, impaired glucose tolerance or diabetes, fasting insulin and leptin levels, and their lipid profile was less favorable. Also, their level of sex hormone-binding globulin was significantly lower and hence their free androgen index was higher, and so was their level of dehydroepiandrosterone sulfate. There was a trend for the study group to have higher ovarian stromal blood flow.

Clinical and biochemical presentations of polycystic ovary syndrome among obese and nonobese women

“…PCOM is identified by pelvic or abdominal ultrasound and defined as R12 follicles in either ovary measuring 2-9 mm in diameter and/or increased ovarian volume >7 mL (13). The prevalence of PCOM has been suggested to be higher than 20% in both Western and Asian women (14,15) and is the most frequently used criterion in PCOS diagnosis (11). Our results showed that 93% of patients diagnosed with the Rotterdam criteria had polycystic ovaries.…”

Ovarian morphology and prevalence of polycystic ovary syndrome in Japanese women with type 1 diabetes mellitus

“…The prevalence of PCOM/PCOS in type 1 diabetes mellitus was similar compared with previous reports 5 . There was a previous study where Chinese women with gestational diabetes mellitus were examined in regard to the prevalence of PCOM and compared with normal women 7 . In that study, the prevalence of PCOM in premenopausal Chinese normal women was 23%.…”

Polycystic Ovary Syndrome in Asian Women

“…Using the revised ultrasound criteria, 5 we compared the prevalence of PCO between 70 Chinese women with previous GDM and 70 age-, parity-, and delivery-year matched women who had a normal oral glucose tolerance test (OGTT) during their index pregnancy. 11 The GDM group had a higher though not statistically significant prevalence of PCO than did the control group (34.0% vs. 23.0%, respectively). Within the GDM group, there was no difference in the metabolic profiles between those with and without PCO, although the body mass index (BMI) and Ferriman-Gallwey score tended to be higher in women with PCO.…”