The prevalence, severity, and risk factors for dry eye disease in Dubai – a cross sectional study

Alkabbani, Sarah; Lakshmanan, Jeyaseelan; Rao, Anupama; Thakur, Sandeep; Warhekar, Pramod

doi:10.1186/s12886-021-01978-4

Cited by 23 publications

(37 citation statements)

References 21 publications

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“…So far, advancing age, female gender, and smoking are the most common factors associated with DED ( 21 ), which were consistent with our findings. However, another population-based investigation in Dubai showed that daily screen time (> 6 h) was positively associated with dry eyes ( 22 , 23 ), while no association between daily screen exposure time and DED was found in this study. This discrepancy might be due to the different lifestyle of the study participants.…”

Section: Discussioncontrasting

confidence: 89%

Dry Eye Disease Among Mongolian and Han Older Adults in Grasslands of Northern China: Prevalence, Associated Factors, and Vision-Related Quality of Life

Zhang

et al. 2021

Front. Med.

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Purpose: Dry eye disease (DED) is projected to have increasing public health burden in China with the aging population. No published studies on the epidemiology of DED have been found in grasslands. We estimated DED prevalence among older adults living in grasslands of northern China and investigated its associated factors and impact on vision-related quality of life (VR-QoL).Methods: A multistage cluster random sampling technique was used to select Mongolian and Han participants aged over 40 from November 2020 to May 2021 in this area. An assessment of DED was performed with Ocular Surface Disease Index (OSDI) questionnaire, Schirmer's I test (ST), and Tear film break up time (TBUT). All the participants completed the Chinese version of National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) assessing VR-QoL.Results: Of the 1,400 enumerated residents, 1,287 were examined. The overall age and gender standardized prevalence of DED was 34.5%, of which, 32.6% of Mongolian and 35.4% of Han had DED. In a multivariate model, statistically significant associations were found with advancing age [odds ratio (OR) 1.03, 95% confidence interval (CI) 1.02–1.04], female gender (OR 1.32, 95% CI 1.04–1.68), smoking (OR 0.7, 95% CI 0.5–0.98), anti-fatigue eye-drop use (OR 0.56, 95% CI 0.41–0.77), milk product intake (OR 0.55, 95% CI 0.39–0.77), number of household members (OR 0.8, 95% CI 0.72–0.88). DED was associated with lower scores on VR-QoL (β= −0.14, P < 0.01). Similar results were observed when analyses were stratified by ethnicity.Conclusions: The novelty-associated factors for DED in the grasslands area were anti-fatigue eye drop use, milk product intake, and number of household members. DED and its components were associated with VR-QoL. Further prospective studies are needed to confirm these findings.

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Section: Discussioncontrasting

confidence: 89%

Dry Eye Disease Among Mongolian and Han Older Adults in Grasslands of Northern China: Prevalence, Associated Factors, and Vision-Related Quality of Life

Zhang

et al. 2021

Front. Med.

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“…As shown in Figure 1 , the prevalence of DED in our participants was 55.9%, the majority of which had mild DED (23.6%). The prevalence is similar to that in a study conducted in Dubai (62.6%) 17 and in the Eastern region of Saudi Arabia (62.4%). 3 However, in a study conducted in Al-Ahsa, the prevalence was lower (32.1%).…”

Section: Discussionsupporting

confidence: 88%

“…3 Conversely, some studies found no significant association between sex and OSDI score. 21 , 22 Although several studies have shown a significant association between age group and DED, 4 , 17 our results revealed no such association.…”

Section: Discussioncontrasting

confidence: 86%

“… 19 Moreover, higher estrogen levels are associated with disturbed tear film production. 17 , 20 We found a significant association between sex and DED symptoms, in which 62.4% of women had DED symptoms compared to 51.9% of men. This is in line with studies conducted in Dubai, 17 Korea, 8 and the Eastern region of Saudi Arabia.…”

Section: Discussionmentioning

confidence: 65%

“… 17 , 20 We found a significant association between sex and DED symptoms, in which 62.4% of women had DED symptoms compared to 51.9% of men. This is in line with studies conducted in Dubai, 17 Korea, 8 and the Eastern region of Saudi Arabia. 3 Conversely, some studies found no significant association between sex and OSDI score.…”

Section: Discussionmentioning

confidence: 65%

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Dry Eye Disease Symptoms and Its Association with Daily Beverage Intake Among Adults in Saudi Arabia

Alsahly¹,

Aldawsari²,

Alzaidy³

et al. 2022

OPTH

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Purpose To evaluate the association between dry eye disease (DED) symptoms and daily beverage intake among adults in Saudi Arabia. Patients and Methods In this cross-sectional, questionnaire-based study, we distributed an online questionnaire to men and women older than 18 years living in Saudi Arabia. The questionnaire consisted of items related to the sociodemographic characteristics of the participants and two validated indices: the Ocular Surface Disease Index (OSDI) and the brief 15-item Beverage Intake Questionnaire (BEVQ-15). Participants were excluded if they were aged less than 18 years; wore contact lenses; had existing eye disease (excluding refractive errors), history of eye surgery (including corrective eye surgeries), or autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, Sjogren’s syndrome); or were currently taking specific medications including antidepressants, antihistamines, and diuretics. Results After applying the study exclusion criteria, a total of 615 participants were included in the statistical analysis. The majority of participants were 18–34 years old (450, 73.2%), and men (381, 62%) exceeded women (234, 38%) by approximately 1.5-fold. OSDI scores showed that 344 participants (55.9%) had DED symptoms, 145 (23.6%) had mild dry eyes; and 106 (17.2%) and 93 (15.1%) had moderate and severe dry eyes, respectively. There was a significant association between sex and DED symptoms (p = 0.012); the frequency of DED symptoms in women exceeded that in men. However, no significant differences were observed with other demographic data such as age and location of residence. Although beverage intake was moderately correlated to OSDI score (R = 0.27), we found no significant association between beverage intake and DED symptoms. Conclusion This is the first study to highlight the association between DED symptoms and daily beverage intake. We found a significant association between DED symptoms and female sex. However, no significant association was found between DED symptoms and other demographic characteristics or beverage intake.

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Estimates of dry eye disease in Saudi Arabia based on a short questionnaire of prevalence, symptoms, and risk factors: The Twaiq Mountain Eye Study I

Alkhaldi

Allam

Radwan

et al. 2023

Contact Lens and Anterior Eye

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The prevalence, severity, and risk factors for dry eye disease in Dubai – a cross sectional study

Cited by 23 publications

References 21 publications

Dry Eye Disease Among Mongolian and Han Older Adults in Grasslands of Northern China: Prevalence, Associated Factors, and Vision-Related Quality of Life

Dry Eye Disease Among Mongolian and Han Older Adults in Grasslands of Northern China: Prevalence, Associated Factors, and Vision-Related Quality of Life

Dry Eye Disease Symptoms and Its Association with Daily Beverage Intake Among Adults in Saudi Arabia

Estimates of dry eye disease in Saudi Arabia based on a short questionnaire of prevalence, symptoms, and risk factors: The Twaiq Mountain Eye Study I

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