Mining technological solutions for underground mining of offbalance gypsum reserves in difficult mining and geological conditions were justified. An analysis of typical geological disturbances of gypsum seams is carried out using the Artemivsk deposit (Ukraine) as an example. Physical and mechanical properties of rocks in disturbed zones are determined. A quantitative assessment of strength characteristics of rocks during their moistening is carried out. The minimum permissible values of the width of the tape pillar and the power of the protective stack above the camera in the presence of a violation in the roof are calculated. The use of selective mining of the lower part of the seam by combines of the “Roadheader” type is recommended. The maximum width and height of the chamber are determined by the type of combine. The technology has been tested and realized at the gypsum mine of the Additional Liability Company “Siniat”.