The problem of uveitis in Bendel State of Nigeria: experience in Benin City.

Ayanru, J O

doi:10.1136/bjo.61.10.655

Cited by 27 publications

(29 citation statements)

References 33 publications

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“…In Africa, Toxoplasmosis has been shown to be the cause of uveitis in 52% of cases in Sierra Leone [16] and similar findings were already reported earlier from Nigeria [17]. A study from the London (UK) area showed that the incidence of ocular toxoplasmosis was 100-times higher in black immigrants born in west Africa as compared with subjects born in the UK [18].…”

supporting

confidence: 71%

Toxoplasmavaccines: appropriate end points and sample size in future human clinical trials

Silveira¹,

Gargano

Kijlstra

et al. 2009

Expert Review of Anti-infective Therapy

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supporting

confidence: 71%

Toxoplasmavaccines: appropriate end points and sample size in future human clinical trials

Silveira¹,

Gargano

Kijlstra

et al. 2009

Expert Review of Anti-infective Therapy

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“…Most of the previous studies reported equal sex distribution (3,4,10,12,20,21). There are, however, studies stating a female (6,13,16,22) or male (9,(23)(24)(25) predominance. Female predominance has been explained by the greater proportion of chronic disease in women (6).…”

Section: Discussionmentioning

confidence: 74%

Epidemiology of uveitis in a referral hospital in Turkey

Özdal¹,

Yazıcı²,

Tüfek³

et al. 2014

Turk J Med Sci

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A series of (E) -3- (3-(2,3-dihydro-3-methyl-2-oxo-3 H -benzoxazole-6-yl)-1-phenyl-1 H -pyrazole-4-yl)acrylamides (7a-k) were synthesized and evaluated for their in vitro inhibitory activities on COX-1 and COX-2 isoforms using a human whole blood assay as well as their antiplatelet profile against human platelet aggregation using arachidonic acid as agonists. Among the synthesized derivatives 7a-k, especially compound 7g exhibited dual anti-inflammatory and antiplatelet activity with selective COX-2 inhibition.

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“…In general population the frequency of HLA-B27 was 14 % in Finland, 8.2 8 in England and 1 % in Japan. There was a practical absence of HLA-B27 and rheumatic AAU among Negroes from West Africa (Ayanru 1977).…”

mentioning

confidence: 99%

Acute Anterior Uveitis and Hla Antigens

Saari

1984

Acta Ophthalmologica

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Different clinical entities of acute anterior uveitis (AAU) may occur due to different pathogenetic, race and geographig conditions. A highly significant association of HLA‐B27 with AAU has been confirmed in different countries. HLA‐B27 associated AAU was associated neither with MLC (HLA‐D) determinants nor with α1‐antitrypsin phenotype MZ. Family studies suggested that a pleiotropic HLA‐B27 linked gene with autosomal dominant inheritance, incomplete penetrance and variable expressivity may determine the susceptibility to AAU. Different infections may trigger AAU in HLA‐B27 positive patients. In the immune response cytotoxic T cells may react simultaneously with the antigen and HLA‐B27 with increased chemotaxis and release of prostaglandins. In Caucasians the pathogenesis of “HLA‐B27 negative” AAU in many cases, e.g. in varicella iritis, may be explained by deposition of circulating immune complexes in the iris. Bilateral nongranulomatous iridocyclitis in black Americans was associated with HLA‐B8 and HLA‐DR5 but this entity showed no systemic disease association.

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The problem of uveitis in Bendel State of Nigeria: experience in Benin City.

Cited by 27 publications

References 33 publications

Toxoplasmavaccines: appropriate end points and sample size in future human clinical trials

Toxoplasmavaccines: appropriate end points and sample size in future human clinical trials

Epidemiology of uveitis in a referral hospital in Turkey

Acute Anterior Uveitis and Hla Antigens

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