The Problem Stud Dog

Lopate, C.

doi:10.1016/j.cvsm.2012.01.014

Cited by 15 publications

(11 citation statements)

References 53 publications

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“…Due to the lack of pathognomonical clinical signs, at least at their onset, in the general dog population, prostatic disorders often go unnoticed, while these abnormalities are diagnosed more frequently in dogs presented for poor fertility evaluation (Polisca et al., ). In this last case, an ultrasonographic examination of the prostate is strongly recommended when a presumptive diagnosis of BPH is based on detection of blood in prostatic fluid of the ejaculate or in case of a presumptive diagnosis of chronic prostatitis based on signs of infertility or decreased libido (Johnston et al., ; Lopate, ).…”

Section: Discussionmentioning

confidence: 99%

“…Due to the lack of pathognomonical clinical signs, at least at their onset, in the general dog population, prostatic disorders often go unnoticed, while these abnormalities are diagnosed more frequently in T A B L E 1 Canine prostate specific esterase (CPSE) serum concentration and measurements of the prostate in the 19 dogs ultrasonographically examined grouped according to presence (Group A) or absence (Group B) of abnormal ultrasonographic findings (altered appearance, cysts or irregular borders) dogs presented for poor fertility evaluation (Polisca et al, 2016). In this last case, an ultrasonographic examination of the prostate is strongly recommended when a presumptive diagnosis of BPH is based on detection of blood in prostatic fluid of the ejaculate or in case of a presumptive diagnosis of chronic prostatitis based on signs of infertility or decreased libido Lopate, 2012).…”

Section: Discussionmentioning

confidence: 99%

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Canine prostate specific esterase (CPSE) as an useful biomarker in preventive screening programme of canine prostate: CPSE threshold value assessment and its correlation with ultrasonographic prostatic abnormalities in asymptomatic dogs

Alonge

Melandri

Leoci

et al. 2017

Reprod Domestic Animals

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Due to the increased attention that pet-owners devote to their animals and to the improved veterinary care, investigations regarding methods to early detect prostatic disorders that might affect canine life quality have been performed. Canine prostate specific esterase (CPSE) concentration was reported to be higher in dogs suffering from prostatic diseases. This study aimed to estimate the CPSE threshold as a biomarker to early identify prostatic diseases in asymptomatic dogs. The ultrasonographic examination of the prostate was performed in 19 dogs (6-40 kg; 1-5 years) with no symptoms of prostatic diseases. Dogs were grouped according to the presence (Group A) or absence (Group B) of prostatic disorders at the ultrasound (altered appearance, the presence of cysts or irregular borders). For each dog, a venous blood sample was collected to measure serum CPSE and the ratio between calculated and normal expected prostatic volume was assessed for each dog. The CPSE data were statistically analysed (t test, p < .05), and the CPSE threshold in blood serum between groups was calculated by ROC. In 11 dogs, ultrasonography showed signs of prostatic abnormalities (Group A, 2-5 years), while no signs were detected in eight dogs (Group B, 1-3 years). The calculated/estimated volume ratio resulted greater than 1.5 in Group A dogs. The CPSE was statistically different between groups (p < .0001): higher in Group A (mean = 184.9, SD = 126 ng/ml) than in Group B (38.9 ± 22.1 ng/ml). The cut-off CPSE threshold was 52.3 ng/ml (ROC, AUC = 0.974, SE 95.6%, SP 89.2%). This study suggests that CPSE serum concentration higher than 50 ng/ml in asymptomatic dogs is associated with ultrasonographic alterations and increased the prostatic size (volume by 1.5 times greater than the normal size). As the onset of prostatic disorders often remains asymptomatic, the rapid assessment of CPSE could be suitable for selecting preventively those animals that would require further accurate evaluation.

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“…Due to the lack of pathognomonical clinical signs, at least at their onset, in the general dog population, prostatic disorders often go unnoticed, while these abnormalities are diagnosed more frequently in dogs presented for poor fertility evaluation (Polisca et al., ). In this last case, an ultrasonographic examination of the prostate is strongly recommended when a presumptive diagnosis of BPH is based on detection of blood in prostatic fluid of the ejaculate or in case of a presumptive diagnosis of chronic prostatitis based on signs of infertility or decreased libido (Johnston et al., ; Lopate, ).…”

Section: Discussionmentioning

confidence: 99%

“…Due to the lack of pathognomonical clinical signs, at least at their onset, in the general dog population, prostatic disorders often go unnoticed, while these abnormalities are diagnosed more frequently in T A B L E 1 Canine prostate specific esterase (CPSE) serum concentration and measurements of the prostate in the 19 dogs ultrasonographically examined grouped according to presence (Group A) or absence (Group B) of abnormal ultrasonographic findings (altered appearance, cysts or irregular borders) dogs presented for poor fertility evaluation (Polisca et al, 2016). In this last case, an ultrasonographic examination of the prostate is strongly recommended when a presumptive diagnosis of BPH is based on detection of blood in prostatic fluid of the ejaculate or in case of a presumptive diagnosis of chronic prostatitis based on signs of infertility or decreased libido Lopate, 2012).…”

Section: Discussionmentioning

confidence: 99%

Canine prostate specific esterase (CPSE) as an useful biomarker in preventive screening programme of canine prostate: CPSE threshold value assessment and its correlation with ultrasonographic prostatic abnormalities in asymptomatic dogs

Alonge

Melandri

Leoci

et al. 2017

Reprod Domestic Animals

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“…Only later, with the progressive enlargement of the prostatic gland, there would be observed a sanguineous discharge from the prepuce or urethra, hematuria, and hemospermia, ribbon-like appearance of feces and sometimes rectal obstruction [ 6 ]. As BPH could impair fertility due to decreased libido or blood detection in the ejaculate, in stud dogs the prostatic disorders are often diagnosed earlier, before the late symptomatic stage occurs [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Clinical Effectiveness of Deslorelin Acetate and Osaterone Acetate in Dogs with Benign Prostatic Hyperplasia

Niżański

Ochota

Fontaine

et al. 2020

Animals

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This article presents the results of a randomized clinical trial, designed to compare the efficacy and therapeutic profiles of YpozaneTM (osaterone acetate—OA) or SuprelorinTM (deslorelin acetate—DA) in male dogs with clinical signs of benign prostate hyperplasia (BPH). Forty-five intact male dogs were used in the study. The Group I (negative control) included 10 healthy dogs, the Group II (positive control) included 10 dogs with confirmed BPH and no treatment, whereas Group III and IV consisted of dogs with BPH and treated either with DA (15 dogs) or OA (10 dogs). The clinical response, testosterone and estradiol levels, hematology, biochemistry, and adverse effects incidence were evaluated. Both OA and DA proved to be effective for BPH treatment in dogs, as they allowed for the clinical remission in all treated dogs. The complete alleviation of BPH symptoms was noticed sooner with the use of OA (in 80% of dogs from day 7) compared to DA (in 40% of dogs within the first 21 days). The recurrence of clinical signs related to BPH was observed from week 24 in dogs treated with OA, whereas no relapse was noticed in dogs treated with DA at the end of the 36 weeks of the observation period. In 5 dogs (33%) treated with DA, a flare-up effect (increase in the clinical signs associated with BPH) was noticed on day 7. Despite individual differences in the clinical action, both medications were effective and safe options for the treatment of symptoms related to BPH in dogs.

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“…Так, дослідники (Lopate, 2012;Beccaglia et al, 2016;Mantziaras et al, 2017) наголошують на важливості обстеження самців перед будь яким видом осіменіння (природне чи штучне) для виявлення патологій відтворної здатності. Рання діагностика дозволить уникнути потенціальних причин безпліддя, таких як захворювання передміхурової залози, сім'яників, епідидимітів та статевого члена травматичного, інфекційного, пухлинного, ендокринного чи аутоімунного походження.…”

Section: обговоренняunclassified

Features of the manifestation in small breed dogs’ reproductive function

Voronov¹,

Skliarov²

2020

Theor. Appl. Vet. Med.

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The andrological clinical examination of small breed dogs was carried out and according to its results, were established the group, breed, age, and performance dependence of the reproductive function manifestation in small breed dogs. The research novelty is that the experiment was carried out on representatives of small breeds such as the Yorkshire Terrier, Chihuahua, Spitz, Toy Terrier, Miniature Poodle, and Maltese lapdog. We found out that residents of megalopolises, such as Dnipro, are more likely to have small and medium-sized dogs, which are more adapted to the conditions of the apartment, and less capricious to the conditions of keeping and care. The reproductive function manifestation of dogs was determined by qualitative indicators of the clinical state, reproductive organs, sexual reflexes, and sperm with distribution on a scale: «G» (good), «S» (satisfactory), «U» (unsatisfactory). After analyzing the data obtained during the study, we came to the conclusion that dogs of small breeds have no less reproductive potential than representatives of other dogs breeds. Of the total number of research dogs, 75% received a grade «G» (good), 22.2% – «S» (satisfactory), 2.8% – «U» (unsatisfactory). The Yorkshire Terrier and Chihuahua have the highest reproductive potential compared to other breeds. In terms of age distribution, the best indicators were shown by representatives of the group from 2 to 3 and from 3 to 5 years. It has been established that the quality of sperm increased depending on the mode use of the male. In particular, according to the intensive use of male dogs (2 times a week, no more than 2 weeks in a row), the reproductive capacity was higher, compared to the moderate and occasional mode of use. The obtained data will help to more expediently use males of small breed dogs in reproduction and have high reproduction rates inside the breed.

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The Problem Stud Dog

Cited by 15 publications

References 53 publications

Canine prostate specific esterase (CPSE) as an useful biomarker in preventive screening programme of canine prostate: CPSE threshold value assessment and its correlation with ultrasonographic prostatic abnormalities in asymptomatic dogs

Canine prostate specific esterase (CPSE) as an useful biomarker in preventive screening programme of canine prostate: CPSE threshold value assessment and its correlation with ultrasonographic prostatic abnormalities in asymptomatic dogs

Comparison of Clinical Effectiveness of Deslorelin Acetate and Osaterone Acetate in Dogs with Benign Prostatic Hyperplasia

Features of the manifestation in small breed dogs’ reproductive function

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