The protective effects of Bacillus licheniformis preparation on gastrointestinal disorders and inflammation induced by radiotherapy in pediatric patients with central nervous system tumor

Oral Supplements of Combined Bacillus licheniformis Zhengchangsheng® and Xylooligosaccharides Improve High-Fat Diet-Induced Obesity and Modulate the Gut Microbiota in Rats

“…According to the Food and Agriculture Organization of the United Nations (FAO) and WHO, probiotics are defined as "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host" [16]. The probiotic Bacillus licheniformis Zhengchangsheng® (BL), which is "generally recognized as safe," has been used extensively as an antiviral and immunoregulatory agent in clinical treatment [17][18][19]. In our previous study, we demonstrate that BL can attenuate dextran sulphate sodium (DSS)-induced colitis and modulate dysbiosis during inflammatory bowel disease (IBD) [20].…”

Pediatric Patients and Dietary Choices: Examining Alternative Options, Decision Making, and Misinformation

“…Probiotics may accompany regimens that include frequent antibiotics or gastrointestinal irritants to assist with side effects, boost immunity, and replenish the normal flora (Patel & Goyal, 2013). Studies indicate that probiotics may be helpful in reducing chemotherapy-and radiation-induced diarrhea and other gastrointestinal side effects (Du et al, 2018;Redman et al, 2014). A study by Du et al (2018) reported the effects of probiotics, specifically Bacillus licheniformis, on pediatric patients with neurologic cancer undergoing radiation therapy.…”

“…Studies indicate that probiotics may be helpful in reducing chemotherapy-and radiation-induced diarrhea and other gastrointestinal side effects (Du et al, 2018;Redman et al, 2014). A study by Du et al (2018) reported the effects of probiotics, specifically Bacillus licheniformis, on pediatric patients with neurologic cancer undergoing radiation therapy. Patients who received probiotics had increased relief of gastrointestinal upset symptoms, such as mucositis, nausea and vomiting, diarrhea, and abdominal pain (Du et al, 2018).…”

“…A study by Du et al (2018) reported the effects of probiotics, specifically Bacillus licheniformis, on pediatric patients with neurologic cancer undergoing radiation therapy. Patients who received probiotics had increased relief of gastrointestinal upset symptoms, such as mucositis, nausea and vomiting, diarrhea, and abdominal pain (Du et al, 2018). The study also measured inflammatory cytokine levels, which were lower in the patients who received probiotics (Du et al, 2018).…”

Carotenoid profile produced by Bacillus licheniformis Rt4M10 isolated from grapevines grown in high altitude and their antioxidant activity

“…B. licheniformis is also used as probiotic (Elshaghabee et al, 2017). The scientific evidence shows their benefits on gastrointestinal disorders and inflammation of animals and humans; as well, it has protective effects in the pediatric patient undergoing radiotherapy (Du et al, 2018). However, despite the various benefit-promoting effects of BL, the importance of carotenoid production has been understudied.…”