“…Indeed, available reviews about mental health among medical students during the pandemic have highlighted high levels of depression, anxiety, stress, and exhaustion, suggesting a rise in those symptoms [ 17 , 18 ]. However, most of studies had a cross-sectional [ 17 ] or a longitudinal design [ 19 , 20 , 21 ] without taking into account pre-pandemic periods, thus not allowing inferring about an actual worsening of mental health conditions compared with pre-pandemic years. To date, very few studies focusing on medical students have presented prospective (repeated cross-sectional or longitudinal) data beginning from a pre-pandemic period [ 22 , 23 , 24 , 25 ].…”