The psychological impact of Behçet's disease

Abstract

Background Bechet's disease (BD), a chronic multiorgan involving disease, has a significant impact on quality of life in spite of effective treatment modalities. Disease manifestations such as arthritis, orogenital ulcerations, rashes, angiitis, and neurological involvement affect health‐related quality of life (HRQoL) through its impact on depression, anxiety, and fatigue. Objectives We aimed explore the psychological impact of BD, taking into consideration the effect on the HRQoL, as well as the association with depression, anxiety, wellbeing, and fatigue. Methods This is a narrative review of the literature that looks into the association of BD on the HRQoL including all studies that have assessed such as association. Results/Findings Depression and anxiety are prevalent among patients with BD, and contribute significantly to fatigue, a common symptom among BD patients. In addition, the psychological wellbeing is affected by the disease, however, more studies are needed to assess this relationship. Conclusion Depression and anxiety are strongly associated with BD, and contribute significantly to fatigue, a common symptom among BD patients. In addition, the psychological wellbeing is affected by the disease, however, more studies are needed to assess this relationship. Besides, the controlling factors of the psychological impact are still to be deciphered.

Association of Behçet’s disease with the risk of metabolic syndrome and its components: a systematic review and meta-analysis

“…Regarding immune disorders, the dysfunction of regulatory T cells also regulates the development of both BD and hypertension [ 43 , 47 ]. Moreover, BD and MetS negatively impact patients’ quality of life and psychological health [ 48 , 49 ]. The inflammatory process of BD and MetS may explain the psychological damage.…”

Tổn Thương Niêm Mạc Đa Cơ Quan Trong Hội Chứng Behçet Báo Cáo Trường Hợp Bệnh

“…Những nghiên cứu cho thấy gần 38,6% bệnh nhân Behçet được chẩn đoán trầm cảm, rối loạn lo lâu, ảnh hưởng giao tiếp xã hội. 11 Hệ quả sau đó gồm rối giấc ngủ, mệt mỏi và giảm hứng thú tình dục. Do vậy, việc khai thác triệu chứng tâm thần kinh cũng như đánh giá thang điểm chất lượng cuộc sống là việc làm cần thiết khi thăm khám người bệnh Behçet.…”

Behçet's yndrome: one year in review 2023

“…anxiety occur more frequently in BS patients than in the general population (80)(81)(82). Young patients and those with low socio-economic status are more severely affected (80).…”