The Quantitative Analysis of Occlusive Peripheral Arterial Disease By a Non-Intrusive Ultrasonic Technique

Gosling, R. G.; Dunbar, Geoffrey; King, D. H.; Newman, D. L.; Side, C.D.; Woodcock, J. P.; Fitzgerald, D. E.; Keates, Jonathan; Macmillan, Douglas

doi:10.1177/000331977102200109

Cited by 418 publications

(158 citation statements)

References 2 publications

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“…This difference in flow velocities reflects downstream resistance, which could at least in part depend on the degree of peripheral arterial stiffness. Originally, PI and RI were introduced by Gosling et al 22 and Pourcelot et al 23 respectively, to detect peripheral vascular disease. Today, PI and RI are mainly measured in the renal arteries to evaluate the severity of renal failure and renal artery stenosis.…”

Section: Discussionmentioning

confidence: 99%

Association between carotid haemodynamics and inflammation in patients with essential hypertension

et al. 2005

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Previous studies have shown that high blood pressure causes chronic inflammation. Hypertensive patients are reported to have high-circulating levels of proinflammatory cytokines such as interleukin-6 (IL-6) and high sensitive C-reactive protein (hs-CRP). The pulsatility index (PI) and resistive index (RI) are used as markers of peripheral vascular resistance. In the present study, we evaluated the relationship between carotid haemodynamics and the proinflammatory cytokines, IL-6 and hs-CRP. In all, 41 patients with essential hypertension participated. The intima-media thickness (IMT), peak systolic velocity (pVs), peak diastolic velocity (pVd) and mean velocity (mV) in the common carotid artery were measured using ultrasound Doppler flow methods, and PI [(pVsÀpVd)/mV] and RI [(pVsÀpVd)/pVs] were calculated. Serum IL-6 and hs-CRP concentrations were measured by an enzyme-linked immunosorbent assay. IMT was positively correlated with age and pulse pressure. Both PI and RI were positively correlated with pulse pressure, IL-6 and hs-CRP. A multiple regression analysis revealed that PI and RI were independently associated with hs-CRP. These results suggested that carotid haemodynamic parameters such as PI and RI are associated with atherosclerosis and inflammation in hypertensive patients.

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Section: Discussionmentioning

confidence: 99%

Association between carotid haemodynamics and inflammation in patients with essential hypertension

et al. 2005

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“…The UA pulsatility index (PI) 15 was increased (> mean + 2 SD according to reference values 16 ) in 26 cases, but end-diastolic flow was maintained in all cases. Since absent or reversed end-diastolic flow in the UA is an indication for a cesarean section (CS) at our unit in term or near term pregnancies, such cases were not exposed to an OCT. 6 The procedure of simultaneous Doppler velocimetry and OCT has previously been described [11][12][13] venous pulsations, the 'worst ever' recorded FVW was chosen.…”

Section: Methodsmentioning

confidence: 98%

Restrained cerebral hyperperfusion in response to superimposed acute hypoxemia in growth-restricted human fetuses with established brain-sparing blood flow

Olofsson

2006

Early Human Development

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“…Pulsatility index and RI are measures of resistance to blood flow and are inversely related to blood flow (10,11). The PI is derived from the difference between the peak systolic velocity (S) and end diastolic velocity (D) divided by mean velocity (Velocity m ) (S-D/Velocity m ) (12). Resistance index is the difference between the peak systolic velocity (S) and end diastolic velocity (D) divided by peak systolic velocity (S-D/S).…”

Section: Methodsmentioning

confidence: 99%

Power Doppler ultrasound assessment of follicular vascularity in the early follicular phase and its relationship with outcome of in vitro fertilization

Shrestha

Costello

Sjöblom

et al. 2006

J Assist Reprod Genet

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Objective : To determine whether ovarian perifollicular blood flow (PFBF) in the early follicular phase (EFP) was associated with treatment outcome. Design : Retrospective longitudinal cohort study. Setting : Tertiary referral centre/university hospital. Patients : Thirty-four women underwent 37 IVF cycles, which resulted in 35 embryo transfers. Interventions : Serial transvaginal scans using power Doppler ultrasound during the follicular phase. Ovarian PFBF of follicles ≥ 5 mm was subjectively assessed using a modified grading system (grades 0-4). Main outcome measures : Ovarian PFBF and pregnancy. Results : Treatment cycles were retrospectively divided into two groups: Group 1 (n = 20) had cycles with at least one small (5-10 mm) or medium (11-14 mm) size follicle(s) of high grade (2-4) PFBF on cycle day 5 or 6 or 7; and Group 2 (n = 17), had cycles that did not. Group 1 had a significantly higher proportion of high grade large follicles in the late follicular phase (35% vs. 21%) (OR 2.0; 95% CI 1.1-3.7) and higher clinical pregnancy rate (47% vs. 12%) (OR 6.3; CI 1.1-35.7) compared to Group 2. Conclusion : High grade ovarian PFBF in the EFP during IVF is associated with both high grade PFBF in the late follicular phase and a higher clinical pregnancy rate.

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The Quantitative Analysis of Occlusive Peripheral Arterial Disease By a Non-Intrusive Ultrasonic Technique

Cited by 418 publications

References 2 publications

Association between carotid haemodynamics and inflammation in patients with essential hypertension

Association between carotid haemodynamics and inflammation in patients with essential hypertension

Restrained cerebral hyperperfusion in response to superimposed acute hypoxemia in growth-restricted human fetuses with established brain-sparing blood flow

Power Doppler ultrasound assessment of follicular vascularity in the early follicular phase and its relationship with outcome of in vitro fertilization

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