In 1934 the authors (1) reported the results of spectroscopic observations on the emission, reflection and transmission of infra-red radiation by the human skin. The experiments were undertaken with the primary purpose of determining -whether the emissive and absorptive properties of the skin were those of black-body radiator within the spectral range in which the human body radiates heat. The results of the experiments, carried out by the use of a reflecting infra-red spectrometer equipped with a rock salt prism, confirmed previously accumulated evidence (2,3,4) as to the truth of this assumption, and thus seemed to establish beyond all doubt the validity of the radiometric method of skin temperature measurement. Recently published results of Christiansen and Larsen (11), using questionable technique, would lead one to the dubious conclusions that the white human skin has a radiating power only about 78 per cent that of a black body and that the skin is quite transparent to the infra-red radiation in the region of the radiation emission from the human body. This new evidence is in direct contradiction to that of the combined work of nearly all other workers on this problem; it will be briefly discussed below. During the course of our previous transmission experiments it was noted that: (1) the penetrability of skin for the near infrared region of 0.75 ,u to 3 u, which is not included in the range of black-body emission above alluded to, was considerably lower as found by us than as reported by the majority of previous observers (5,6,7,8,9,10) and (2) the transmission spectrum of the thinnest layers of skin showed an apparently characteristic fine structure which resembled that of the infra-red spectrum of many organic compounds, and its most prominent bands were thought to be due to the C-H, N-H and 0-H linkages in the organic substances composing the skin.The present report is of further experiments concerned principally with these two findings of the former investigation. Since nearly all observers agree that it is only within the near infrared range than any appreciable penetration of the skin occurs, it is this portion of the spectrum, if any, which is effective in the deep penetration of radiant heat. As the present use of infra-red therapy is based partially on the supposition that the infra-red radiation penetrates in effective amounts, it was thought desirable to repeat the observations on living skin as well as on dead skin, on which alone our previous observations had been made. To determine more exactly the amount of scattered transmitted radiation, thus determining accurately the total amount of transmitted radiation, is also of importance. This range of wave lengths also includes those effective in infra-red photography, and the question of how far and in what quantities the radiation penetrates is of importance in determining the limitations of this method of photographing subcutaneous structures.As regards the second of the findings, i.e. the presence of characteristic absorption bands in the tra...